Personalized aerobic exercise training for heart disease patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial focuses on improving aerobic fitness in patients with coronary artery disease (CAD) through personalized exercise training. A total of 105 participants will be randomly assigned to one of three training intensity levels: moderate, heavy, or severe. The study will assess participants' physiological and health metrics at baseline and after 7 and 14 weeks of training, which will occur three times a week on a cycle ergometer. The goal is to determine the effectiveness of tailored exercise intensity in enhancing fitness and overall health outcomes for CAD patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with CAD who do not have any identified left ventricular dysfunction (i.e., left ventricular ejection fraction \[LVEF\] \<50%) and who: were discharged from the hospital following admission for acute coronary syndrome (i.e., ST-elevation or non ST-elevation myocardial infarction, addressed with PCI or CABG, as documented by their attending physician; referred to St. Joseph's CRSP Program; completed a CPET at the St. Joseph's CRSP Program (as routine screening for cardiac rehabilitation) and have been cleared to exercise in a structured format (i.e., do not exhibit any contraindications to maximal exercise); without: respiratory or musculoskeletal issues that would prohibit them from cycling exercise.

Exclusion Criteria:

* Those who have: diagnosed heart failure, severe aortic stenosis, congenital coronary abnormality, 2-3° atrioventricular block, major arrhythmias such as atrial fibrillation (including paroxysmal), or are scheduled to undergo PCI or CABG surgery within 2 months following hospital discharge; are using insulin for diabetes; diagnosed with respiratory disease; or musculoskeletal issues that prohibit cycling exercise; and/or are unable to provide informed consent..

Where it's running

• The University of Western Ontario
  London, Ontario, Canada Recruiting

Study contacts

• Study coordinator: Daniel A Keir, PhD
• Email: dkeir@uwo.ca
• Phone: 519-661-2111

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.