Personalized adapted exercise program for advanced melanoma
Official title: APA (Adapted Physical Activity) for Patients With Advanced Melanoma APA (Adapted Physical Activity) for Patients With Advanced Melanoma Undergoing Treatment: Evaluation of a Personalized Program at the Hospital
Run by University Hospital, Rouen · NCT07031830 · Data updated 2026-11-12
This will try a personalized adapted physical activity program for adults with advanced melanoma who are receiving immunotherapy or targeted therapy.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | University Hospital, Rouen Academic / other |
| Drugs / interventions | immunotherapy, nivolumab, ipilimumab |
| Locations | 1 site (Rouen) |
| Status | Recruiting |
| Started | November 18, 2024 |
| Main results expected | November 18, 2028 |
| Study ends | January 2, 2029 |
| Registry record updated | June 22, 2025 |
| Trial ID | NCT07031830 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) with advanced melanoma treated with immunotherapy or targeted therapy at the participating center who agree to the adapted sports module and can complete a six-month follow-up.
✕Probably not a fit
Patients with melanoma not requiring systemic treatment, minors, those unable to complete six-month follow-up, or legally protected/incapacitated persons are not eligible and are unlikely to benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational hospital-based program offering a personalized adapted physical activity (APA) module to adults with advanced melanoma treated with systemic therapies. Patients who agree to participate receive tailored exercise recommendations and follow-up within the hospital care pathway. Outcomes tracked over about six months include physical capacity, cancer-related fatigue, and quality of life measures. The program responds to growing survivorship in metastatic melanoma and aims to limit physical deconditioning during treatment.
Why it matters
Potential benefit: If successful, the program could help maintain or improve physical capacity, reduce cancer-related fatigue, and preserve quality of life during systemic treatment.
How similar studies have gone: Exercise and adapted physical activity programs have shown benefits for fatigue, strength, and quality of life in cancers such as breast and prostate and have been feasible in metastatic patients, but specific data in advanced melanoma are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or female patient aged 18 or older * Advanced melanoma treated adjuvantly or curatively with immunotherapy or targeted therapy * Patient who has read and understood the information letter and does not object to participating in the study * Member of or beneficiary of a social security scheme * Patients who have agreed to participate in the adapted sports module Exclusion Criteria: * Minor patient * Melanoma not requiring systemic treatment * Condition making 6-month follow-up impossible * Protected incapacitated persons (judicial protection, guardianship, curatorship, deprivation of liberty)
Where it's running
-
University Rouen Hospital
Rouen, France Recruiting
Study contacts
- Study coordinator: David DM MALLET, Director
- Email: David.Mallet@chu-rouen.fr
- Phone: 02 32 88 82 65
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.