Personalized 4-week nutrition and activity program for people after esophageal cancer surgery

Developing an Ecological and Tailored Nutritional Intervention to Improve Quality of Life in Esophageal Cancer Survivors

Not applicable Interventional Samsung Medical Center · NCT07024849

This 4-week program will try personalized nutrition plans, customized care foods, step-tracking, and weekly phone counseling to see if they help people who had surgery for esophageal cancer feel better and eat more comfortably.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years and up
SexAll
SponsorSamsung Medical Center Academic / other
Locations1 site (Seoul, Seoul)
Trial IDNCT07024849 on ClinicalTrials.gov

What this trial studies

Participants will receive a 4-week, theory-based ecological nutrition intervention tailored to individual post-esophagectomy needs, including written nutrition guidelines, customized care foods, a wearable device to encourage walking, and weekly telephone counseling. Outcomes measured before and after the program include food intake, adherence to dietary guidance, activity level, nutritional indices (such as PNI and NRI), weight change, fatigue, symptom burden, quality of life, and satisfaction with meals and services. The study also includes post-intervention interviews to capture patient experiences and assess clinical feasibility. The approach emphasizes practical, individualized supports to address common nutritional and functional challenges after esophageal cancer surgery.

Who should consider this trial

Good fit: Adults (18+) who speak Korean natively, had or plan to have curative-intent esophagectomy and reconstruction for stage 1–3 esophageal cancer at diagnosis, and who consent to participate (family members may also be included).

Not a fit: Patients with concurrent recent other-organ cancers, major cognitive or communication limits, persistent inability to progress to oral feeding or requiring ileostomy/enteral-only feeding, or substantially reduced renal function (eGFR <60 mL/min/1.73 m2) are unlikely to benefit from this program.

Why it matters

Potential benefit: If successful, the program could improve nutritional status, reduce fatigue and symptoms, and enhance quality of life and meal satisfaction for esophageal cancer survivors.

How similar studies have performed: Nutrition and activity interventions have improved outcomes in other cancer survivor populations, but tailored ecological programs specifically for post-esophagectomy patients are relatively novel and less well studied.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with clinical stage 1-3 primary esophageal cancer at diagnosis who have planned or received treatment, including esophageal resection and reconstruction, with curative intent, and their families\*.
* You are at least 18 years of age
* Have a native-level understanding of Korean
* Who consented to this study

Exclusion Criteria:

* Concurrent multiple cancers at the time of diagnosis or a history of diagnosed and treated other organ cancers within the past year at the time of diagnosis
* Have had esophageal resection and reconstruction surgery for other reasons before being diagnosed with esophageal cancer
* Persons with limited cognitive and communication abilities
* The patient has had problems progressing to oral feeding after surgery, requiring a concurrent ileostomy, or the investigator determines that an interventional study is not appropriate.
* Individuals with reduced renal function for whom protein intake is not recommended (estimated GFR \<60 mL/min/1.73 m2)
* People who are unable to walk due to joint problems, paralysis, etc.
* Those who do not use smartphones

Where this trial is running

Seoul, Seoul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Esophageal Cancernutritional interventionnutritionsurvivorsesophageal cancercare foodshealth behaviorecological intervention
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.