Personality traits and learning an oro‑esophageal voice after laryngectomy

Correlation Between Personnality Traits and Ability to Learn Oroesophageal Voice

Not applicable Interventional Assistance Publique Hopitaux De Marseille · NCT06856863

This will test whether certain personality traits help people who had a laryngectomy learn an oro‑esophageal voice.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years and up
SexAll
SponsorAssistance Publique Hopitaux De Marseille Academic / other
Locations1 site (Marseille)
Trial IDNCT06856863 on ClinicalTrials.gov

What this trial studies

After total laryngectomy some patients can learn an oro‑oesophageal voice (VOO) with speech therapy while others cannot. This single‑center study in Marseille will administer the Temperament and Character Inventory (TCI‑125) to 40 eligible patients and compare personality scores between those who succeed and those who do not in acquiring VOO after at least six months of therapy. Eligible participants are adults who had laryngectomy or total pharyngo‑laryngectomy 6 months to 5 years earlier, are French‑speaking, and have a MoCA score ≥16. The goal is to identify personality profiles associated with successful VOO acquisition to help guide rehabilitation strategies.

Who should consider this trial

Good fit: Adults (≥18) who underwent laryngectomy or total pharyngo‑laryngectomy 6 months to 5 years ago, are French‑speaking, have MoCA ≥16, and have had at least six months of VOO speech therapy within the past five years.

Not a fit: Patients with anatomical or physiological barriers to VOO (for example esophageal stenosis), those who never received adequate speech therapy, or those operated on more than five years ago are unlikely to benefit from the findings.

Why it matters

Potential benefit: If successful, the findings could help predict who is most likely to learn VOO and allow clinicians to personalize speech‑rehabilitation approaches.

How similar studies have performed: Older reports suggested psychological factors influence VOO learning but lacked standardized personality measures, so applying the TCI‑125 is a relatively novel, quantitatively focused approach with limited prior evidence of success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Men or women over 18 years of age
* French-speaking patients
* MoCA score ≥ 16/30
* Patients who have undergone laryngectomy or total pharyngo-laryngectomy between 6 months and 5 years of age
* Patients who have agreed to learn VOO
* Patients who began speech therapy to learn VOO no more than five years ago
* Patients who have had access to speech therapy to learn VOO for at least six months (completed or ongoing)
* Patients who have received information about the study and have not expressed their opposition
* Patients who are beneficiaries of or entitled to social security coverage

Exclusion Criteria:

* Patients who underwent a laryngectomy or total pharyngolaryngectomy more than 5 years ago
* Patients who did not receive speech therapy to learn OVO postoperatively, or who received less than 6 months of therapy
* Patients with a related condition that prevents them from learning VOO (anatomical or physiological abnormality, esophageal stenosis)
* Patients with a related condition that may be responsible for speech or fluency disorders (developmental, organic, or functional speech and language disorders, stuttering, stammering, fluency disorders, neurological speech disorders)
* Patients with uncorrected hearing loss
* Patients unable to receive informed consent about the ongoing research due to impaired psychological or physical health
* MoCA score \<16/30
* Patients with definite depressive symptoms (HAD-D score ≥ 11)
* Patients in a period of exclusion from another research protocol at the time of collection of the non-opposition.
* Subjects covered by articles L1121-5 to 1121-8 of the French Public Health Code (minors, adults under guardianship or trusteeship, patients deprived of their liberty, pregnant or breast-feeding women, etc.).

Where this trial is running

Marseille

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions LaryngectomyTotal Pharyngo-laryngectomy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.