Perioral rejuvenation with hyaluronic acid to reduce perioral lines and restore lip fullness

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, non-interventional observational program enrolling adults who are already planning routine perioral rejuvenation at a single clinic in Vienna. Participants receive whatever holistic perioral procedure their treating clinician chooses, with no additional mandated treatments. Independent assessors will rate lip fullness and static perioral lines and VISIA imaging will document skin wrinkling and surface roughness at baseline, Week 6, and Week 12. The main outcome is the proportion of participants with at least a 1-point improvement on both the Lip Fullness Scale and the Static Perioral Lines Assessment Scale at Week 12, with secondary measures of volume and patient satisfaction over 6 and 12 weeks.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. 18 years or older at time of treatment.
2. At least mild static perioral lines and maximum of thin lips, as assessed by the investigator.
3. Participant has a stable medical condition with no uncontrolled systemic disease.
4. Willingness to participate in the routine follow-up after 12 weeks and a signed ICF.
5. Participant already visiting the clinic for the specific treatment.

Exclusion Criteria:

1. Pregnancy and breast feeding.
2. Known impairment of blood coagulation.
3. Presence of acute infection or inflammation at the proposed injection sites.
4. Hyaluronic Acid-Filler treatment in the perioral area within the last 6 months.
5. Patients with a history of autoimmune disease or who are receiving immune therapy.
6. History of hypersensitivity to hyaluronic acid, lidocaine hydrochloride or other amidetype local anaesthetics.

Where it's running

• Yuvell
  Vienna, State of Vienna, Austria Recruiting

Study contacts

• Study coordinator: Mia Cajkovsky
• Email: mia.cajkovsky@yuvell.at
• Phone: +43 1 512 13 25 30

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.