Perianal disease and its impact on sexual life
The "Hidden Morbidity" of Perianal Disease: A Prospective Evaluation of Psychosexual Health and Body Image.
This project will see how chronic perianal conditions (like fistulas, perianal Crohn’s, or pilonidal disease) affect sexual function and self‑esteem in adults who can complete Greek questionnaires.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | AHEPA University Hospital Academic / other |
| Locations | 1 site (Thessaloniki, Thessaloniki) |
| Trial ID | NCT07519850 on ClinicalTrials.gov |
What this trial studies
This is a prospective, cross-sectional observational assessment of adults with chronic perianal disease presenting to a proctology clinic. Participants complete a one-time questionnaire battery including IIEF-5 for men, FSFI-6 for women, and a 10-item "Hidden Morbidity" PROM to measure sexual function, body image, and related distress. Data on disease etiology, symptoms, presence of setons, and surgical history will be collected to explore associations with psychosexual outcomes. No experimental interventions are performed and care follows standard clinical practice.
Who should consider this trial
Good fit: Adults (age >18) with chronic perianal disease (fistula-in-ano, perianal Crohn’s disease, pilonidal disease, or related conditions) who can read and complete the Greek IIEF-5/FSFI-6 and the study PROM and who provide informed consent.
Not a fit: People with active colorectal or anal cancer, major pelvic surgery within the past three months, significant cognitive impairment, or those unable to complete the Greek questionnaires are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, the findings could help clinicians better address sexual health and body-image concerns and improve patient counseling and holistic care for people with perianal disease.
How similar studies have performed: Previous literature has documented psychosexual impacts of perianal disease, but few prospective, questionnaire-based studies have quantified these effects using standardized PROMs, so this work builds on limited prior evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of chronic perianal disease (fistula-in-ano, pCD, pilonidal). * Age \>18 years. * Ability to understand and complete the Greek versions of the IIEF-5/FSFI-6 and the study PROM. * Signed informed consent. Exclusion Criteria: * Active malignancy (colorectal or anal cancer). * Major pelvic surgery in the last 3 months (unrelated to perianal disease). * Cognitive impairment preventing survey completion.
Where this trial is running
Thessaloniki, Thessaloniki
- AHEPA University General Hospital — Thessaloniki, Thessaloniki, Greece (Recruiting)
Study contacts
- Study coordinator: Moysis G. Moysidis, MD, MSc, PhD
- Email: mmoisidis@ahepahosp.gr
- Phone: 00306936071666
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.