Pembrolizumab drug monitoring to help treat non‑small cell lung cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will follow adults with NSCLC who are receiving pembrolizumab (as monotherapy or in combination) at two French hospitals. Blood samples will be taken via the patient's existing peripheral catheter, PICC, or implantable port to measure pembrolizumab concentrations and potentially related biomarkers. Investigators will correlate drug levels with clinical outcomes such as tumor response and treatment-related toxicity without altering standard care. No experimental treatments are given and treatment decisions remain with the treating physician.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years or more
* patient with NSCLC
* pembrolizumab treatment (monotherapy or not) with a placed line (peripheral catheter, PICC or implantable port)

Exclusion Criteria:

* objection to participate in the study
* patient under judicial protection

Where it's running

• Angers University Hospital
  Angers, France Recruiting
• CH Le Mans
  Le Mans, France Not yet recruiting

Study contacts

• Study coordinator: Guillaume DREVIN, Doctor
• Email: Guillaume.Drevin@chu-angers.fr
• Phone: 0241354551

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.