Pelvic floor muscle rehabilitation with desmopressin for children with bedwetting
Official title: Evaluating the Efficacy of Structured Pelvic Floor Muscle Rehabilitation Combined With Desmopressin in the Management of Primary Monosymptomatic Nocturnal Enuresis in Children
Run by Bahçeşehir University · NCT06883851 · Data updated 2026-11-12
This study is testing if combining pelvic floor muscle exercises with a medication can help children aged 7 to 13 who wet the bed at night have fewer accidents and stay dry longer.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 7 Years to 13 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Bahçeşehir University Academic / other |
| Locations | 2 sites (Istanbul, Beşiktaş and 1 other locations) |
| Status | Recruiting |
| Started | March 11, 2025 |
| Main results expected | March 11, 2027 |
| Study ends | August 30, 2027 |
| Registry record updated | March 19, 2025 |
| Trial ID | NCT06883851 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children aged 7 to 13 who have been diagnosed with primary monosymptomatic nocturnal enuresis within the last six months.
✕Probably not a fit
Patients with neurological disorders, anatomical anomalies in the urinary system, or those who have received other enuresis treatments in the last six months may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the effectiveness of Structured Pelvic Floor Muscle Rehabilitation (SPFMR) combined with desmopressin treatment in children aged 7 to 13 diagnosed with Primary Monosymptomatic Nocturnal Enuresis (PMNE). The study aims to determine if SPFMR can reduce the frequency and severity of bedwetting episodes and lower relapse rates compared to a control group receiving only desmopressin. Participants will undergo a randomized controlled approach to assess the impact of this combined treatment over both short- and long-term follow-ups.
Why it matters
Potential benefit: If successful, this approach could significantly improve the management of bedwetting in children, leading to better quality of life.
How similar studies have gone: While the combination of pelvic floor rehabilitation and desmopressin is a novel approach, similar studies have shown promise in treating nocturnal enuresis with various interventions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being between 7 and 13 years old * Diagnosed with primary MNE by a pediatric urology department within the last 6 months * No urinary tract infection verified by laboratory tests * Ability to communicate in Turkish and absence of mental deficit * No diagnosed psychiatric problems * Willingness to participate in the study (child and family) Exclusion Criteria: * Presence of orthopedic conditions preventing evaluation * Anatomical anomalies in the urinary system * History of urinary system surgery * Neurological disorders * Presence of mental retardation * History of orthopedic surgery that could alter pelvic or lower extremity integrity * Receiving PFM rehabilitation in the last 6 months * Using nighttime alarm therapy in the last 6 months * Receiving any treatment for enuresis in the last 6 months
Where it's running
-
Private Selcuk Silay Pediatric Urology Clinic
Istanbul, Beşiktaş, Turkey (Türkiye) Recruiting -
Medipol Acıbadem Region Hospital
Istanbul, Kadıkoy, Turkey (Türkiye) Not yet recruiting
Study contacts
- Principal investigator: Aygul Koseoglu Kurt, Ph.D. (c) — Bahçeşehir University
- Study coordinator: Aygul Koseoglu Kurt, Ph.D. (c), PT
- Email: aygulkoseoglu@gmail.com
- Phone: +90 544 477 0157
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Omegapres versus solifenacin plus mirabegron for children with primary mono‑symptomatic nocturnal enuresis
This tests whether a daily combination of solifenacin and mirabegron reduces nightly bedwetting more than Omegapres in children with primary mono‑symptomatic nocturnal enuresis.
-
Relaxation-based bladder training device for children with daytime wetting, frequent urination, or bedwetting
This trial will test whether a new relaxation-based device helps children with daytime urinary incontinence, urinary frequency, or primary nocturnal enuresis improve bladder control.
-
Individualized pelvic floor rehab added to standard urotherapy and alarm therapy for kids with bedwetting
This trial tests whether adding personalized pelvic floor muscle training to standard alarm therapy helps reduce dry nights in children aged 5–18 with primary monosymptomatic nocturnal enuresis.
-
Bedtime device restriction plus desmopressin for bedwetting in kids
This trial tests whether limiting screen time at night helps desmopressin work better for children with primary monosymptomatic nocturnal enuresis.
-
Using electrical stimulation to treat bedwetting in children
This study is testing if a new electrical stimulation treatment can help children aged 5-17 who struggle with bedwetting after other methods haven't worked.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.