Patient-centered multidisciplinary medication review for frail older adults
Applying a Multidisciplinary Intervention for Drug Adequacy in a Intermediate Care Hospital (AMIDA-ICH)
This project tests whether a team-led, patient-centered medication review by geriatricians, pharmacists, and nurses can reduce the number of medicines taken by frail older adults admitted to an intermediate care hospital.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Parc Sanitari Pere Virgili Academic / other |
| Locations | 1 site (Barcelona, Barcelona) |
| Trial ID | NCT07015112 on ClinicalTrials.gov |
What this trial studies
Older adults admitted to an intermediate care hospital receive a comprehensive geriatric assessment and a structured medication review focused on their goals and clinical characteristics. The multidisciplinary intervention is delivered by geriatricians, clinical pharmacists, and nurses and is compared with the usual medication revision performed by a clinical pharmacist alone. Participants complete questionnaires about their health status and attitudes, and any medication-related adverse events are recorded. The main outcome is change in treatment adequacy, including the average number of medications per patient.
Who should consider this trial
Good fit: Ideal candidates are Spanish-speaking adults aged 65 or older with three or more chronic conditions who are admitted to the intermediate care hospital and can consent (or have a surrogate to consent).
Not a fit: Patients with very short expected hospital stays, limited life expectancy under three months, those who are homeless, or those unable to provide consent are unlikely to benefit from this intervention.
Why it matters
Potential benefit: If successful, this approach could reduce unnecessary medications, lower the risk of adverse drug events, and better align treatments with patients' goals.
How similar studies have performed: Previous multidisciplinary and pharmacist-led deprescribing interventions have often reduced medication counts and inappropriate prescriptions in older adults, although effects on clinical outcomes like hospitalizations and mortality have been mixed.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * older adults (65+ years) * ≥ 3 or more chronic conditions requiring medical therapy * able to speak Spanish * capacity to provide informed consent or have a surrogate able to consent on their behalf Exclusion Criteria: * unable to provide informed consent * anticipated length of hospital stay \< 72h * estimated life expectancy \< 3 months * homeless * already enrolled in a drug trial
Where this trial is running
Barcelona, Barcelona
- Parc Sanitari Pere Virgili — Barcelona, Barcelona, Spain (Recruiting)
Study contacts
- Study coordinator: Ana M de Andrés Lázaro, Pharmacist. PhD
- Email: amandres@perevirgili.cat
- Phone: +34932594128
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.