Patient-centered cervical cancer screening and treatment linkage program in Nairobi

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Clinics in Nairobi are randomized to implement a multi-component care package (DADA LINK) that uses clinic-based care coordinators and the WEMA mHealth platform to improve HPV self-sampling uptake, screening follow-up, and linkage to treatment for precancerous cervical lesions. Trained study staff will abstract routine clinic records to monitor screening, triage, and treatment rates over a 12-month intervention period with an additional 6-month follow-up to measure costs and maintenance. Care coordinators will support clinic staff to follow cervical cancer care guidelines and will collect patient exit surveys to track intervention fidelity and uptake. The intervention was selected after formative qualitative work and clinic mapping to address barriers at the patient, provider, and facility levels in Nairobi.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- Women ages 25-49 years

Exclusion Criteria:

* Pregnant women
* Women ≤6 weeks postpartum
* Women already confirmed to have cervical cancer

Where it's running

• Kenyatta National Hospital
  Nairobi, Kenya Recruiting

Study contacts

• Principal investigator: Rose J Kosgei, MBChB,MMed,MSc,Fell.GynOnc,PhD — University of Nairobi
• Study coordinator: Agnes K Karume, MBChB, MBA, MPH
• Email: karumeagnes@gmail.com
• Phone: +254715181283

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Q-Pad menstrual-pad test to detect high-risk HPV and cervical precancer

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• HPV self-sampling to improve cervical screening for women in Zaporizhzhia during the war

  This project will test whether giving women aged 30–60 in Zaporizhzhia HPV self-sampling kits can keep cervical screening going when clinic access is disrupted by the war.

  Recruiting Karolinska Institutet · Zaporizhzhya · NCT07275333

• AI chatbot plus home HPV self-sampling to boost cervical screening participation

  This project will try to see if sending HPV self-sampling kits to women aged 30–65 in low-income areas together with a multi-language AI chatbot decision aid increases screening uptake among women who did not respond to an initial invitation.

  Recruiting International Agency for Research on Cancer · Carcassone · NCT05286034

• Cervical screening and care options for women living with HIV who test positive for high-risk HPV

  This study tests different ways to screen and manage high-risk HPV in women with HIV to see what might work best for them.

  Recruiting University of California, San Diego · Nairobi · NCT07925307

• Hydrogel spacer to protect the rectum during cervical cancer radiotherapy

  This study tests whether placing an absorbable hydrogel spacer between the cervix/vagina and rectum before definitive radiotherapy can reduce rectal radiation exposure for women with cervical cancer.

  Recruiting Tianjin Medical University Cancer Institute and Hospital · Tianjin, Tianjin Municipality · NCT07904182

• How cinema sessions during chemotherapy might help cervical cancer patients

  We’re testing if watching films during chemotherapy helps cervical cancer patients feel less anxious and improve quality of life.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Roma · NCT07902180

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.