Partnership with patients at risk of cancer
Official title: Total Cancer Care Protocol: A Lifetime Partnership With Patients Who Have or May be at Risk of Having Cancer (ORIEN)
Run by University of Colorado, Denver · NCT03617939 · Data updated 2026-11-12
This study is collecting blood, tissue, and other samples from cancer patients and those at risk to see how it can help improve cancer care and support future research.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 20000 (estimated) |
| Sponsor | University of Colorado, Denver Academic / other |
| Locations | 6 sites (Aurora, Colorado and 5 other locations) |
| Status | Recruiting |
| Started | September 16, 2015 |
| Main results expected | September 2035 |
| Study ends | September 2037 |
| Registry record updated | November 10, 2025 |
| Trial ID | NCT03617939 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals aged 18 and older who have been diagnosed with cancer or are at risk for cancer.
✕Probably not a fit
Patients who are part of vulnerable populations, such as children or cognitively impaired individuals, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to create a comprehensive collection of biological samples and associated data from patients diagnosed with cancer or at risk of developing cancer. The Oncology Research Information Exchange Network (ORIEN) will gather blood, tissue, and other biological samples, along with survey data and medical records, to enhance the understanding of cancer risk and improve standard care. The ultimate goal is to facilitate future clinical trials and advancements in personalized medicine for cancer patients.
Why it matters
Potential benefit: If successful, this initiative could lead to improved early detection and personalized treatment options for cancer patients.
How similar studies have gone: Other studies focusing on biospecimen collection and data integration have shown promise in advancing cancer research, indicating that this approach is both relevant and potentially impactful.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. 18 years of age and older. 2. Diagnosed with cancer, or may be at risk for cancer. 3. Able to understand and sign the TCCP Informed Consent and Research Authorization form directly or through a legally authorized representative (LAR). Non-English speaking subjects will also be invited to participate in the TCCP study, in accordance with COMIRB's short-form consent use. Exclusion Criteria: 1\. Members of vulnerable populations including neonates (birth to 30 days), children (under age 18), wards of the State, prisoners or those on probation or alternate sentencing, or decisionally challenged (adults or children that are cognitively impaired, incompetent to consent, proxy consent, or consenting in life threatening situations).
Where it's running
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University of Colorado Hospital
Aurora, Colorado, United States Recruiting -
UCHealth Memorial Hospital Central
Colorado Springs, Colorado, United States Recruiting -
UCHealth Memorial Hospital North
Colorado Springs, Colorado, United States Recruiting -
Cherry Creek Medical Center
Denver, Colorado, United States Recruiting -
UCHealth Poudre Valley Health System
Fort Collins, Colorado, United States Recruiting -
Highlands Ranch Medical Center
Highlands Ranch, Colorado, United States Recruiting
Study contacts
- Principal investigator: Virginia Borges, MD — University of Colorado, Denver
- Study coordinator: Kyra Anderson
- Email: kyra.anderson@cuanschutz.edu
- Phone: 303-724-3868
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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A program to collect cancer-related samples and data for better cancer care
This study is collecting blood, tissue, and other samples from people with cancer or at risk of it to help improve cancer care and treatment in the future.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.