Partnering with a peer to improve responses to brief health programs

Partnering to Enhance Emerging Adults' Response to Programs (PEER)

Not applicable Interventional UConn Health · NCT06115252

We will test whether doing a short motivational-interviewing program together with a peer changes brain activity and alcohol-related behaviors over a year in emerging adults.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment248 (estimated)
Ages18 Years to 19 Years
SexAll
SponsorUConn Health Academic / other
Locations1 site (Dallas, Texas)
Trial IDNCT06115252 on ClinicalTrials.gov

What this trial studies

Participants and a peer come for a single Participation Day during which each person first completes questionnaires on their own, then they complete a brief motivational interviewing–based health program together. During the visit participants undergo functional MRI while completing tasks designed to probe brain responses to the intervention. The team will contact each participant individually at 3, 6, and 12 months to track health behaviors over time. Standard MRI exclusions (e.g., unremovable metal, pregnancy), left-handedness, and history of major neurological illness or prolonged loss of consciousness are reasons for exclusion.

Who should consider this trial

Good fit: Emerging adults who can attend an in-person Participation Day with a peer, are eligible for MRI scanning, agree to follow-up contacts, and provide informed consent are the intended participants.

Not a fit: People who cannot have an MRI (including those with metal implants or who are pregnant), are left-handed, have major neurological disorders, or cannot bring a peer are unlikely to participate or benefit from this protocol.

Why it matters

Potential benefit: If successful, this approach could lead to peer-based programs that change brain responses and reduce risky alcohol-related behaviors in young adults.

How similar studies have performed: Motivational interviewing and peer-involved interventions have shown mixed but promising effects on young adult drinking, while combining peer co-participation with fMRI to study mechanisms is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* within the specified age range
* agree to be contacted for the 3, 6, and 12 month follow ups
* provide fully informed consent

Exclusion Criteria:

* left-handed
* evidence of brain injury/illness and/or neurological, neurodevelopmental disorder including psychosis and related medications (e.g., antipsychotics; neuroleptics)
* loss of consciousness ≥ 2 minutes
* other fMRI contraindications (e.g., unremovable metal on/in body, pregnant)

Where this trial is running

Dallas, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Alcohol Use, Unspecified
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.