Partial pulpotomy outcomes for mature molars with moderate versus severe pulpitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional trial enrolls patients aged 15–40 with mature permanent mandibular molars and extremely deep caries who respond to pulp sensibility testing and whose bleeding can be controlled within 10 minutes. Participants receive a partial pulpotomy and are classified into moderate or severe pulpitis groups, with clinical and radiographic success checked at 6 and 12 months. Secondary outcomes include oral health–related quality of life and daily postoperative pain recorded for one week. All treatments and follow-up visits are conducted at the Postgraduate Institute of Dental Sciences, Rohtak.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients aged 15-40 years.
2. Mature permanent mandibular molars with extremely deep caries on radiograph, giving positive response to pulp sensibility test.
3. For Moderate Pulpitis- strong, heightened and prolonged reaction to cold, which can last for minutes, possibly percussion sensitive and spontaneous dull pain that can be more or less suppressed with pain medication.

   For Severe Pulpitis- Severe spontaneous pain and clear pain reaction to warmth and cold stimuli, often, sharp to dull throbbing pain, patients have trouble sleeping because of the pain (gets worse when lying down). Tooth is very sensitive to touch and percussion.
4. Pulpal bleeding can be controlled within 10 minutes
5. Patients having normal periapical status with periapical index (PAI) score ≤ 2
6. Periodontally healthy teeth
7. Positive response to pulp sensibility test

Exclusion Criteria:

1. Non restorable teeth
2. Negative response to vitality testing
3. Presence of sinus tract or soft tissue swelling
4. Absence of deep carious lesions radiographically
5. Radiographic signs of internal or external root resorption
6. Patient had moderate to severe pain, but preferred root canal treatment
7. Presence of sound dentin over pulp and pulp not exposed intraoperatively
8. Pulp haemorrhage could not be arrested within 10 minutes.
9. Necrotic pulp evident upon exposure
10. Pregnant women
11. Absence of antagonist teeth

Where it's running

• PGIDS Rohtak
  Rohtak, Haryana, India Recruiting

Study contacts

• Principal investigator: Dr. Pankaj Sangwan, MDS — PGIDS, Rohtak, Haryana 124001
• Study coordinator: Dr. Pankaj Sangwan, MDS
• Email: drps_1@yahoo.co.in
• Phone: 9996112202

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Pulpal inflammation and full pulpotomy outcomes in deeply carious mandibular molars

  This study tests whether levels of inflammatory markers IL-1β and IL-6 in deeply decayed mandibular molars predict the success of a full pulpotomy in adults with moderate to severe pulpitis.

  Recruiting Postgraduate Institute of Dental Sciences Rohtak · Rohtak, Haryana · NCT07825415

• Partial pulpotomy in mature lower molars with SIP using calcium hypochlorite vs sodium hypochlorite

  This trial tests whether washing the exposed pulp with calcium hypochlorite or with sodium hypochlorite during partial pulpotomy in adults helps healing and reduces pain.

  Recruiting Postgraduate Institute of Dental Sciences Rohtak · Rohtak, Haryana · NCT07748676

• Direct pulp capping for deep and extremely deep caries in mature molars with reversible pulpitis

  This study tests whether direct pulp capping works similarly for deep versus extremely deep caries in adult, mature mandibular molars with reversible pulpitis.

  Recruiting Postgraduate Institute of Dental Sciences Rohtak · Rohtak, Haryana · NCT07696702

• Direct pulp capping in lower molars with side (proximal) versus top (occlusal) cavities: does the cavity location matter?

  This research will test whether direct pulp capping works as well for lower molars with side (proximal) cavities as for those with top (occlusal) cavities in people aged 15–40 who have reversible pulpitis.

  Recruiting Postgraduate Institute of Dental Sciences Rohtak · Rohtak, Haryana · NCT07578662

• Pulpotomy versus root canal treatment for extremely deep caries

  This study tests whether full pulpotomy works as well as root canal treatment for people aged 12 and older with extremely deep caries treated in a university dental clinic.

  Recruiting National University Hospital, Singapore · Singapore · NCT07242742

• Egyptian MTA and Biodentine versus Calcium Hydroxide for indirect pulp capping in permanent teeth

  This will test whether Egyptian MTA or Biodentine work better than calcium hydroxide for indirect pulp capping in adults with deep cavities to help keep the tooth's pulp healthy.

  Recruiting Phase 4 Cairo University · Cairo · NCT06683833

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.