Parental plans and pregnancy outcomes in 93 women with Turner syndrome
Parental Project Amongst 93 Patients With Turner Syndrome
This project describes parental plans and pregnancy outcomes for adult women with Turner syndrome treated at Strasbourg University Hospitals between 2009 and 2019.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 93 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | Female |
| Sponsor | University Hospital, Strasbourg, France Academic / other |
| Locations | 1 site (Strasbourg) |
| Trial ID | NCT07344012 on ClinicalTrials.gov |
What this trial studies
This observational, retrospective review examines medical records of 93 adult women with karyotype-confirmed Turner syndrome who expressed a desire to become parents and were seen at Strasbourg University Hospitals from January 1, 2009 to December 31, 2019. The study records occurrences of spontaneous pregnancies, pregnancies after egg donation, adoptions, and cases excluded for missing data or lack of desire for parenthood. No interventions are assigned; data are summarized and compared across relevant clinical subgroups. The goal is to provide real-world frequencies and outcomes to inform clinical counseling about parenthood options in Turner syndrome.
Who should consider this trial
Good fit: Adult women (≥18 years) with karyotype-confirmed Turner syndrome who sought parenthood and were treated at Strasbourg University Hospitals during 2009–2019.
Not a fit: People who did not want to become parents, who lack sufficient medical records, or who were not treated at Strasbourg University Hospitals are unlikely to benefit directly from these findings.
Why it matters
Potential benefit: If successful, this work could help clinicians give clearer, evidence-based counseling about realistic parenthood options for women with Turner syndrome.
How similar studies have performed: Previous observational reports indicate spontaneous pregnancies are uncommon and pregnancies after egg donation are more frequent in Turner syndrome, so this study complements existing descriptive literature rather than introducing a novel therapy.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult women (≥18 years old) * Treated at Strasbourg University Hospitals for a parental project during the period from January 1, 2009, to December 31, 2019 * Having presented with Turner syndrome confirmed by karyotyping * Having expressed a desire to become a parent during consultation Exclusion Criteria: * No desire to become a parent or missing data * Missing data
Where this trial is running
Strasbourg
- Service d'Endocrinologie, Diabétologie, Nutrition - CHU de Strasbourg - France — Strasbourg, France (Recruiting)
Study contacts
- Study coordinator: Thibault BAHOUGNE, MD
- Email: thibault.bahougne@chru-strasbourg.fr
- Phone: 33 3.88.12.78.99
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.