Parental plans and pregnancy outcomes in 93 women with Turner syndrome
Official title: Parental Project Amongst 93 Patients With Turner Syndrome
Run by University Hospital, Strasbourg, France · NCT07344012 · Data updated 2026-11-12
This project describes parental plans and pregnancy outcomes for adult women with Turner syndrome treated at Strasbourg University Hospitals between 2009 and 2019.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | Women only |
| Enrollment | 93 (estimated) |
| Sponsor | University Hospital, Strasbourg, France Academic / other |
| Locations | 1 site (Strasbourg) |
| Status | Recruiting |
| Started | November 18, 2025 |
| Main results expected | November 2027 |
| Study ends | November 18, 2027 |
| Registry record updated | January 15, 2026 |
| Trial ID | NCT07344012 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adult women (≥18 years) with karyotype-confirmed Turner syndrome who sought parenthood and were treated at Strasbourg University Hospitals during 2009–2019.
✕Probably not a fit
People who did not want to become parents, who lack sufficient medical records, or who were not treated at Strasbourg University Hospitals are unlikely to benefit directly from these findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational, retrospective review examines medical records of 93 adult women with karyotype-confirmed Turner syndrome who expressed a desire to become parents and were seen at Strasbourg University Hospitals from January 1, 2009 to December 31, 2019. The study records occurrences of spontaneous pregnancies, pregnancies after egg donation, adoptions, and cases excluded for missing data or lack of desire for parenthood. No interventions are assigned; data are summarized and compared across relevant clinical subgroups. The goal is to provide real-world frequencies and outcomes to inform clinical counseling about parenthood options in Turner syndrome.
Why it matters
Potential benefit: If successful, this work could help clinicians give clearer, evidence-based counseling about realistic parenthood options for women with Turner syndrome.
How similar studies have gone: Previous observational reports indicate spontaneous pregnancies are uncommon and pregnancies after egg donation are more frequent in Turner syndrome, so this study complements existing descriptive literature rather than introducing a novel therapy.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult women (≥18 years old) * Treated at Strasbourg University Hospitals for a parental project during the period from January 1, 2009, to December 31, 2019 * Having presented with Turner syndrome confirmed by karyotyping * Having expressed a desire to become a parent during consultation Exclusion Criteria: * No desire to become a parent or missing data * Missing data
Where it's running
-
Service d'Endocrinologie, Diabétologie, Nutrition - CHU de Strasbourg - France
Strasbourg, France Recruiting
Study contacts
- Study coordinator: Thibault BAHOUGNE, MD
- Email: thibault.bahougne@chru-strasbourg.fr
- Phone: 33 3.88.12.78.99
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Inpegsomatropin vs Givopegsomatropin for short stature in girls with Turner syndrome
A 52-week, multicenter, randomized study tests whether Inpegsomatropin injections help prepubertal girls with Turner syndrome grow taller compared with a known treatment.
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Once-weekly lonapegsomatropin versus daily somatropin for children and adolescents with short stature due to growth-hormone-sufficient conditions
It will test whether a once-weekly injection of lonapegsomatropin helps children and teens with Turner syndrome, SHOX mutation, small-for-gestational-age, or idiopathic short stature grow as well as or better than daily somatropin.
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Bleeding patterns with sequential versus continuous progesterone in adolescents with Turner syndrome
This study will test whether taking progesterone continuously or in a sequential (monthly) schedule changes bleeding patterns in adolescents with Turner syndrome who are on estrogen replacement therapy.
-
Investigating liver health in adults with Turner Syndrome
This study looks at liver health in adults with Turner Syndrome to see how common liver problems are and what might cause them.
-
Exercise testing in girls with Turner Syndrome
This study tests how well girls aged 8-18 with Turner Syndrome can exercise by measuring their heart and lung performance during a special exercise test.
-
Comparing oral and transdermal estrogen therapy in women with Turner syndrome
This study is testing whether taking estrogen as a pill or through the skin is better for women with Turner syndrome in terms of their overall health and well-being.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.