Parent-led intervention for children with autism

Effectiveness of PACT Intervention, Delivered by Parents, Guided by Videoconference, on the Autism of Their Children With ASD

Not applicable Interventional Hôpital le Vinatier · NCT04244721

This study is testing whether a parent-led communication program delivered through video calls can help young children with autism improve their communication skills better than standard care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment212 (estimated)
Ages18 Months to 36 Months
SexAll
SponsorHôpital le Vinatier Academic / other
Locations1 site (Bron)
Trial IDNCT04244721 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of the Preschool Autism Communication Therapy (PACT) when delivered by parents through videoconferencing for children with Autism Spectrum Disorder (ASD) aged 18 to 36 months. Parents will receive guidance from professionals to enhance communication and synchrony with their children, practicing the techniques at home. The study compares outcomes between children receiving this intervention and those receiving usual care, measuring autism severity using the ADOS-2 scale after 12 months. The aim is to make effective early interventions more accessible, especially in underserved areas.

Who should consider this trial

Good fit: Ideal candidates are children aged 18 to 36 months diagnosed with Autism Spectrum Disorder and exhibiting moderate to severe symptoms.

Not a fit: Patients with severe comorbid conditions or those already receiving intensive autism interventions may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve communication and developmental outcomes for children with autism.

How similar studies have performed: Previous studies have shown positive outcomes for parent-mediated interventions in autism, suggesting this approach could be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Child with autism Spectrum disorder

* Symptoms in autism with a severity superior to 4 as measure by ADOS-2
* Positive ADI (Autism Diagnostic Interview)
* Diagnostic done by a multidisciplinary team
* Nonverbal IQ above 12 months Having health assurance

Exclusion Criteria:

For the child

* Child with a twin brother or sister with ASD or having a brother or sister already included in this study
* Epilepsy requiring medication
* Severe hearing or visual impairment
* Identification of a genetic anomaly causes participation in the intervention or validity of the data (determined by the principal investigator on a case-by-case basis)

For the parents

* Severe hearing or visual impairment
* Severe psychiatric disorder
* Unstable somatic disorders preventing intervention
* Lack of Internet access
* Parent not available for regular follow-up
* Opposition of one parent to the child's participation in a study
* Already receiving PACT therapy or any other intensive intervention (e.g. Denver)

Where this trial is running

Bron

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Autism Spectrum Disorderinterventions Early Start Denver ModelPreschool Autism Communication Therapy
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.