Palliative radiotherapy for advanced non-operable rectal cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the effects of hypofractionated palliative radiotherapy in patients with advanced non-operable rectal cancer. Eligible patients, who are not candidates for surgical resection due to factors like age and comorbidities, will receive a total dose of 39Gy delivered in 13 sessions over 17 days. The study will assess symptomatic responses, particularly focusing on rectal bleeding and pain, as well as report any acute toxicity experienced by the patients. The methodology includes careful patient positioning and preparation to minimize radiation exposure to surrounding organs.

Why it matters

Who can join: the full rules

Inclusion criteria :

1. Patients with rectal or sigmoidal cancer who were not candidates for surgical resection because advanced age, comorbidities, or multiple synchronous metastases at the time of diagnosis
2. Patients with = or \> 18 years old
3. Patients treated with a radiotherapy dose of 39Gy in 13 fractions of 3 Gy

Exclusion criteria:

1. Patients with a non rectum or sigma colo-rectal cancer.
2. Patients with \<18 years old.
3. Patients treated with concurrent chemotherapy
4. Patients candidates for surgical resection after radiotherapy

Where it's running

• Consorci Sanitari de Terrassa
  Terrassa, Catalonia, Spain Recruiting

Study contacts

• Principal investigator: Joan Lozano, MD — Consorci Sanitari de Terrassa
• Study coordinator: Joan Lozano, MD
• Email: jlozano@cst.cat
• Phone: +34 937003690

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.