Pain relief techniques for breast surgery

Analgesic Efficacy of Ultrasound Guided Serratus Anterior Plane Block and Pectoral Nerve Block II Compared to Thoracic Epidural Block After Unilateral Modified Radical Mastectomy

Not applicable Interventional Al-Azhar University · NCT06188156

This study tests two new pain relief methods for women having breast surgery to see if they can help manage pain better than the usual treatment.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment99 (estimated)
Ages35 Years to 65 Years
SexFemale
SponsorAl-Azhar University Academic / other
Drugs / interventionschemotherapy
Locations1 site (Cairo)
Trial IDNCT06188156 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of ultrasound-guided serratus anterior plane block and pectoral nerve block II in managing postoperative pain for women undergoing modified radical mastectomy. It aims to improve pain control and enhance recovery after surgery by comparing these regional anesthesia techniques to the traditional thoracic epidural block. The study will involve administering local anesthetics to specific nerve regions to provide targeted analgesia, potentially reducing the incidence of chronic pain following surgery.

Who should consider this trial

Good fit: Ideal candidates for this study are women aged 35-65 with a BMI between 18.5 and 25, classified as ASA I-II.

Not a fit: Patients with coagulopathy, chronic pain history, or mental health disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce postoperative pain and improve recovery outcomes for breast cancer surgery patients.

How similar studies have performed: Other studies have shown promising results with similar regional anesthesia techniques, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Women aged 35-65 years.
* BMI 18.5 - 25 kg/m2.
* American Society of Anesthesiologists (ASA) I-II.

Exclusion Criteria:

* Patient refusal.
* Coagulopathy.
* Mental and psychiatric disorders.
* History of chronic pain.
* Hypersensitivity or contraindication to any of study drugs
* Previous chemotherapy.

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions AnesthesiaRadical Mastectomythoracic epidural blockageUltrasound Guided Serratus Anterior Plane BlockPectoral Nerve Block II
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.