Pain relief from dental blocks in emergency department patients
Official title: Efficacy of ED Provider-Performed Dental Block for Pain Relief in Patients Presenting With Dental Pain
Run by University of California, San Francisco · NCT05351099 · Data updated 2026-11-12
This study is testing if dental blocks can quickly relieve pain for adults with dental issues who come to the emergency department.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 195 (estimated) |
| Sponsor | University of California, San Francisco Academic / other |
| Locations | 1 site (Fresno, California) |
| Status | Recruiting |
| Started | March 11, 2022 |
| Main results expected | March 11, 2026 |
| Study ends | March 11, 2026 |
| Registry record updated | February 28, 2025 |
| Trial ID | NCT05351099 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older presenting to the emergency department with dental pain who are eligible for a dental nerve block.
✕Probably not a fit
Patients who have had a dental block within the last 24 hours or those unable to provide informed consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational cohort study aims to assess the effectiveness of dental blocks in providing immediate pain relief for patients presenting with dental pain in the emergency department. Conducted at the Community Regional Medical Center, the study will involve trained medical personnel administering dental blocks to eligible adult patients. The study will track patient responses to pain relief and gather data on the effectiveness of this standard care procedure. Participation will be voluntary, and reasons for refusal will be documented without patient identifiers.
Why it matters
Potential benefit: If successful, this study could enhance pain management strategies for patients with dental pain in emergency settings.
How similar studies have gone: While similar approaches have been utilized in pain management, this specific observational study is novel in its focus on dental blocks in an emergency department setting.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients (\>= 18-years-old) presenting to Community Regional Medical Center emergency department with a complaint of dental pain in whom the ED practitioner plans to perform a dental nerve block Exclusion Criteria: * Patient with previous dental block within 24 hours prior to arrival at the ED * Refusal of dental block * Patient in law enforcement custody * Patient unable to be properly informed of study purpose or able to complete pain VAS score due to physical/ mental condition (altered mental status, unstable psychiatric patient) * Patient unable to be properly informed of study purpose or able to complete pain VAS score due to language barrier (not English- or Spanish-speaking) * Patient with other acute non-dental painful condition making evaluation of dental pain severity vs non-dental pain severity not possible * Patient with pain in multiple areas of mouth needing dental block in \> 1 anatomic area * Patient to have Dental / OMFS ED consult for procedure
Where it's running
-
Community Regional Trauma and Burn Center
Fresno, California, United States Recruiting
Study contacts
- Principal investigator: Brian Chinnock, MD — University of California, San Francisco
- Study coordinator: Brian Chinnock, MD
- Email: brian.chinnock@ucsf.edu
- Phone: 559-499-6440
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
CYT-1010 in healthy volunteers and after third molar extraction
This trial tests CYT-1010, at single rising doses, for safety and tolerability in healthy adults and in people experiencing pain after removing wisdom teeth.
-
Compare how much pain kids feel during local anesthesia with what a parent thinks they feel
This study tests whether a parent can accurately gauge their child’s pain during local anesthesia during dental treatment.
-
Local dexamethasone to improve anesthesia in painful irreversible pulpitis
This trial tests whether giving dexamethasone under the gum or between tooth-supporting ligaments helps make anesthetic blocks work better and reduce pain in adults with painful irreversible pulpitis in the lower molars.
-
Intraligamentary injection versus inferior alveolar nerve block for painful lower molar pulpitis
This trial will see if an intraligamentary injection or an inferior alveolar nerve block gives better pain control for adults having root canal treatment of a painful lower molar with symptomatic irreversible pulpitis.
-
Near‑infrared photobiomodulation for pain relief during children's dental care
This will test a non‑invasive near‑infrared light device to reduce tooth and gum pain and potentially avoid injections for children aged 6–12 undergoing routine dental care.
-
Using specialized MRI for dental imaging
This study is testing a new type of MRI specifically for dental imaging to see if it can better diagnose dental problems compared to regular imaging methods.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.