Pain management techniques for heart valve replacement surgery
Ultrasound-guided Modified Transversus Thoracic Muscle Plane Block and Erector Spinal Muscle Plane Block in Heart Valve Replacement Surgery With Median Incision
This study is testing two new pain management techniques during heart valve replacement surgery to see if they can help patients feel less pain and recover better afterward.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Shanghai East Hospital of Tongji University Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Trial ID | NCT06469073 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of ultrasound-guided modified transversus thoracic muscle plane block and erector spinal muscle plane block for providing analgesia during heart valve replacement surgery performed through a median incision. The aim is to assess the impact of these techniques on hemodynamic stability, total analgesic use, perioperative pain levels, and stress responses in patients undergoing this type of surgery. By improving pain management, the study seeks to enhance postoperative recovery and reduce complications associated with inadequate pain control.
Who should consider this trial
Good fit: Ideal candidates are patients aged 18-75 with a BMI of 18-25 kg/m2, classified as ASA II-III and NYHA II-III, scheduled for mitral or aortic valve replacement surgery.
Not a fit: Patients with severe comorbidities, such as preoperative ejection fraction less than 40%, complicated coronary heart disease, or those requiring additional surgical interventions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve pain management and recovery outcomes for patients undergoing heart valve replacement surgery.
How similar studies have performed: Previous studies have shown promising results with similar analgesic techniques in cardiac surgery, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients (18-75 years) with BMI at 18-25 kg/m2, ASA Ⅱ- Ⅲ and NYHA Ⅱ-Ⅲ who scheduled to undergo mitral valve or aortic valve replacement surgery. Exclusion Criteria: * a second operation, preoperative ejection fraction (EF) \< 40%, complicated coronary heart disease, intra-aortic balloon counterpulsation (IABP) support, psychiatric abnormalities, history of allergy to anesthetic drugs, liver or kidney dysfunction, coagulation abnormality, endocrine system diseases and metabolic diseases.
Where this trial is running
Shanghai, Shanghai Municipality
- Shanghai East Hospital of Tongji University — Shanghai, Shanghai Municipality, China (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.