Pain management approach for knee replacement surgery
Continuous Infusion and Intermittent Bolus Adductor Canal Block for Total Knee Arthroplasty
This study tests if a new way of delivering local anesthetics can help people recovering from knee replacement surgery feel less pain and use fewer opioids.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 66 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | National Cheng-Kung University Hospital Academic / other |
| Locations | 1 site (Tainan) |
| Trial ID | NCT05518513 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of a continuous infusion combined with intermittent bolus of local anesthetics for adductor canal block in patients undergoing total knee arthroplasty. The goal is to assess whether this method can provide better pain relief and reduce opioid consumption compared to traditional longer interval bolus techniques. By targeting specific nerve branches responsible for pain during recovery, the study aims to enhance patient outcomes and facilitate rehabilitation. Participants will receive bupivacaine as part of their pain management protocol.
Who should consider this trial
Good fit: Ideal candidates are adults undergoing unilateral total knee arthroplasty under spinal anesthesia with an ASA classification of 1-3.
Not a fit: Patients with chronic pain, long-term opioid use, or neuromuscular diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve pain management and recovery for patients undergoing knee replacement surgery.
How similar studies have performed: Previous studies have shown promising results with adductor canal blocks, suggesting that this approach may be effective, though this specific method is being tested for the first time.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults receiving unilateral total knee arthroplasty under spinal anesthesia * American society of anesthesiologists 1-3 Exclusion Criteria: * Could not cooperate * Allergy to medicines used in the study * Chronic pain * Long term opioid use * Neuromuscular disease * Surgical complication: massive bleeding, postoperative ICU, unanticipated procedure
Where this trial is running
Tainan
- National Cheng Kung University Hospital — Tainan, Taiwan (Recruiting)
Study contacts
- Principal investigator: Wei-Teng Weng, Md — Department of Anesthesiology, National Cheng Kung University Hospital, Taiwan
- Study coordinator: Wei-Teng Weng, MD
- Email: n100390@mail.hosp.ncku.edu.tw
- Phone: +886-6-2353535
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.