Oxytocin's effect on how people react when escaping a moving threat

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In a double-blind, between-subject design, healthy participants receive either 24 IU intranasal oxytocin or placebo and complete a dynamic predator–prey escape task in an fMRI scanner. The task varies predator attack speed while participants choose when and where to flee toward a refuge, yielding measures like flight initiation distance and distance to refuge. The study also records skin conductance responses, confidence and anxiety ratings during the task, and a battery of baseline questionnaires. Brain activity during the escape decisions is measured with MRI to link behavioral and physiological responses to neural mechanisms.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Healthy subjects without past or current psychiatric or neurological disorders

Exclusion Criteria:

* History of head injury; pregnant, menstruating, taking oral contraceptives; medical or psychiatric illness,
* The presence of metal in the body or claustrophobia.

Where it's running

• University of Electronic Science and Technology of China
  Chengdu, Sichuan, China Recruiting

Study contacts

• Principal investigator: Shuxia Yao, Dr — University of Electronic Science and Technology of China
• Study coordinator: Keith M Kendrick, Dr
• Email: k.kendrick.uestc@gmail.com
• Phone: 86-28-61830811

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.