Oxytocin effects on fairness and prosocial choices in healthy adults
Official title: The Modulatory Effects of Oxytocin on Fairness Perception and Related Prosocial Behaviors
Run by University of Electronic Science and Technology of China · NCT07815496 · Data updated 2026-11-12
This study tests whether intranasal oxytocin changes how healthy adults view fairness and act prosocially in economic games.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 35 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | University of Electronic Science and Technology of China Academic / other |
| Locations | 1 site (Chengdu, Sichuan) |
| Status | Recruiting |
| Started | September 5, 2026 |
| Main results expected | December 30, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | September 11, 2026 |
| Trial ID | NCT07815496 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Healthy adults without current or past psychiatric or neurological disorders willing to participate in fMRI procedures.
✕Probably not a fit
Individuals with metal implants, claustrophobia, pregnancy, or other exclusion criteria may not benefit from or be eligible for this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will give healthy adults a single nasal dose of oxytocin or placebo in a randomized, double-blind design while they complete the Dictator Game and Ultimatum Game inside an fMRI scanner. Participants rate perceived fairness and guilt for different offers before choosing to accept or reject them, allowing examination of cognitive and emotional processing related to fairness. Brain activity and behavior will be recorded to understand how oxytocin may modulate decision-making in gain and loss contexts. The study aims to clarify the neural mechanisms by which oxytocin could influence social decision-making in fairness-related situations.
Why it matters
Potential benefit: If successful, this work could inform how oxytocin-based approaches might influence social decision-making in contexts involving fairness.
How similar studies have gone: Prior work suggests oxytocin can modulate social behavior, but findings vary and mechanisms in fairness processing are still being explored.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy subjects without past or current psychiatric or neurological disorders. Exclusion Criteria: * History of head injury; pregnant, menstruating, taking oral contraceptives; medical or psychiatric illness. * The presence of metal in the body or claustrophobia.
Where it's running
-
University of Electronic Science and Technology of China (UESTC)
Chengdu, Sichuan, China Recruiting
Study contacts
- Principal investigator: Shuxia Yao, Dr — University of Electronic Science and Technology of China
- Study coordinator: Shuxia Yao, Dr
- Email: yaoshuxia@uestc.edu.cn
- Phone: 86+18111297596
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.