Clinical trial Recruiting at 1 site Interventional Ages 18 to 35

Oxytocin effects on fairness and prosocial choices in healthy adults

Official title: The Modulatory Effects of Oxytocin on Fairness Perception and Related Prosocial Behaviors

Run by University of Electronic Science and Technology of China · NCT07815496 · Data updated 2026-11-12

This study tests whether intranasal oxytocin changes how healthy adults view fairness and act prosocially in economic games.

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Quick facts

Study typeInterventional
Ages18 Years to 35 Years
SexAll
Enrollment80 (estimated)
SponsorUniversity of Electronic Science and Technology of China
Academic / other
Locations1 site (Chengdu, Sichuan)
StatusRecruiting
StartedSeptember 5, 2026
Main results expectedDecember 30, 2026
Study endsDecember 31, 2026
Registry record updatedSeptember 11, 2026
Trial IDNCT07815496 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Healthy adults without current or past psychiatric or neurological disorders willing to participate in fMRI procedures.

Probably not a fit

Individuals with metal implants, claustrophobia, pregnancy, or other exclusion criteria may not benefit from or be eligible for this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will give healthy adults a single nasal dose of oxytocin or placebo in a randomized, double-blind design while they complete the Dictator Game and Ultimatum Game inside an fMRI scanner. Participants rate perceived fairness and guilt for different offers before choosing to accept or reject them, allowing examination of cognitive and emotional processing related to fairness. Brain activity and behavior will be recorded to understand how oxytocin may modulate decision-making in gain and loss contexts. The study aims to clarify the neural mechanisms by which oxytocin could influence social decision-making in fairness-related situations.

Why it matters

Potential benefit: If successful, this work could inform how oxytocin-based approaches might influence social decision-making in contexts involving fairness.

How similar studies have gone: Prior work suggests oxytocin can modulate social behavior, but findings vary and mechanisms in fairness processing are still being explored.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Healthy subjects without past or current psychiatric or neurological disorders.

Exclusion Criteria:

* History of head injury; pregnant, menstruating, taking oral contraceptives; medical or psychiatric illness.
* The presence of metal in the body or claustrophobia.

Where it's running

  • University of Electronic Science and Technology of China (UESTC)
    Chengdu, Sichuan, China
    Recruiting

Study contacts

  • Principal investigator: Shuxia Yao, Dr — University of Electronic Science and Technology of China
  • Study coordinator: Shuxia Yao, Dr
  • Email: yaoshuxia@uestc.edu.cn
  • Phone: 86+18111297596

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.