Oxytocin and real-time fMRI neurofeedback of the anterior insula

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind, placebo-controlled study enrolls 80 healthy male participants who self-administer either 24 IU intranasal oxytocin or placebo. All participants receive continuous real-time fMRI neurofeedback from the left anterior insula across four training sessions and one transfer session without feedback. Behavioral effects are measured with pain-empathy ratings after each block and interoceptive accuracy is measured with a heartbeat detection/counting task before and after training. Personality and interoception-related traits are assessed with validated questionnaires to explore individual differences in neurofeedback response.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Healthy subjects without any past or present psychiatric or neurological disorders.

Exclusion Criteria:

* History of brain injury medical or mental illness.
* Contraindication to MRI scanning (e.g., metal implants, claustrophobia or other --conditions that make them inappropriate for MRI scanning).

Where it's running

• University of Electronic Science and Technology of China
  Chengdu, Sichuan, China Recruiting

Study contacts

• Study coordinator: Shuxia Yao, Dr
• Email: yaoshuxia@uestc.edu.cn
• Phone: 18111297596

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.