Oxygenated gel treatment for oral ulcers
Efficacy of Oxygenated Gel Therapy in the Management of Oral Aphthous Ulcers: A Randomized Controlled Clinical Trial
This study tests whether an oxygenated gel can help heal mouth ulcers better than a corticosteroid paste in people who have these painful sores.
Quick facts
| Phase | Phase2; Phase3 |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Sex | All |
| Sponsor | British University In Egypt Academic / other |
| Locations | 1 site (Al Sherouk City, Cairo Governorate) |
| Trial ID | NCT06910579 on ClinicalTrials.gov |
What this trial studies
This clinical trial compares the effectiveness of an oxygenated gel and a corticosteroid paste in treating chronic aphthous ulcers. Patients are divided into two groups, with one group applying the oxygenated gel twice daily and the other using a corticosteroid paste four times daily for a week. The study aims to evaluate the healing process and symptom relief at various intervals post-treatment. Both groups consist of patients with single, clinically diagnosed ulcers measuring 6 mm or less.
Who should consider this trial
Good fit: Ideal candidates are systemically healthy individuals with a single chronic aphthous ulcer measuring 6 mm or less.
Not a fit: Patients with multiple ulcers, major aphthous stomatitis, or those with systemic diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could provide a more effective and less invasive option for managing painful oral ulcers.
How similar studies have performed: Previous studies have shown varying success with topical treatments for aphthous ulcers, but the specific use of oxygenated gel is less commonly tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinically diagnosed patients with chronic aphthous stomatitis measuring ≤6 mm in size in the oral cavity and who gave written consent for participation. * Only single ulcers were considered for the study. * Systemically healthy patients. Exclusion Criteria: * The study excluded patients with a history of associated systemic disease. * Cases of chronic aphthous stomatitis (major), lesions of herpetic form, numerous aphthae, and smoking. * Patients with a history of hypersensitivity to the used agents. * Pregnancy and lactation
Where this trial is running
Al Sherouk City, Cairo Governorate
- British University in Egypt — Al Sherouk City, Cairo Governorate, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.