Outcomes of Uterine Conservation in Placenta Accreta Spectrum
Official title: Short and Intermediate Term Outcomes of Uterine Conservation After Cesarian Section in Cases of Placenta Accreta Spectrum
Run by Alexandria University · NCT04866888 · Data updated 2026-11-12
This study looks at how well uterine conservation procedures work for women with placenta accreta spectrum by tracking their recovery, blood loss, and menstrual return after the surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 40 Years |
| Sex | Women only |
| Enrollment | 120 (estimated) |
| Sponsor | Alexandria University Academic / other |
| Locations | 1 site (Alexandria, Alexandria Governorate) |
| Status | Recruiting |
| Started | April 28, 2021 |
| Main results expected | December 1, 2025 |
| Study ends | March 15, 2026 |
| Registry record updated | February 12, 2025 |
| Trial ID | NCT04866888 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are pregnant women diagnosed with singleton placenta accreta spectrum who are scheduled for elective cesarean section.
✕Probably not a fit
Patients requesting hysterectomy or those with significant coexisting uterine pathologies may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on patients diagnosed with placenta accreta spectrum who undergo uterine conservation procedures. It aims to document the immediate outcomes of these procedures, including success rates, blood loss, and transfusion requirements. Participants will be monitored for the return of menstruation and any uterine abnormalities through ultrasound or hysteroscopy. Data will be collected on various factors such as obstetric history, anthropometry, and laboratory investigations to assess the overall impact of the intervention.
Why it matters
Potential benefit: If successful, this study could improve management strategies for placenta accreta spectrum, potentially preserving fertility and reducing complications.
How similar studies have gone: While there have been studies on placenta accreta spectrum, this specific approach to uterine conservation is relatively novel and may provide new insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Diagnosed sonographically to have placenta accreta spectrum. * Pregnancy is singleton and fetus is alive. * Elective caesarean section done from 35 gestational weeks. Exclusion Criteria: * • Patients requesting hysterectomy. * Coexisting uterine pathology such as fibroids or gynaecological malignancies. * Patients with bleeding diathesis. * Morbid obesity of BMI \>40. * Patients having labour pains or vaginal bleeding before scheduled intervention.
Where it's running
-
Faculty of Medicine
Alexandria, Alexandria Governorate, Egypt Recruiting
Study contacts
- Study coordinator: Omar Y Elshorbagy, As.lec
- Email: o_kamal13@alexmed.edu.eg
- Phone: 01111362322
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Vision Transformer–based ultrasound AI to detect placenta accreta spectrum
A AI tool uses ultrasound video inputs to help see if the placenta is abnormally attached during pregnancy in women at risk.
-
Three conservative surgeries for placenta accreta spectrum: a comparison
Researchers compare three uterus-preserving surgical options to see which works best for placenta accreta spectrum.
-
Planned cesarean at 37 weeks versus 36 weeks for pregnancies with placenta previa and accreta
We will test whether scheduling cesarean delivery at 37 weeks instead of 36 weeks helps newborns without increasing maternal bleeding in pregnant women with placenta previa and accreta.
-
High versus low segmental hysterotomy and uterine scar defects after a first cesarean
We will test whether high or low segmental hysterotomy, with or without cross-suturing, leads to fewer uterine scar defects in people having their first cesarean.
-
Managing placenta accreta spectrum while preserving the uterus
This study is testing a new way to manage placenta accreta spectrum disorders by allowing some women to keep their uterus after delivery instead of having surgery, to see if it can be a safer option for them.
-
An anatomical system to guide surgery for placenta accreta
This project will try using an intraoperative anatomical classification to help surgeons choose the safest operation for pregnant people at risk of placenta accreta.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.