Outcomes after CAR-T and radiation therapy for blood cancers

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study collects data on patients with hematologic malignancies who are receiving chimeric antigen receptor therapy (CAR-T) and radiation therapy. It aims to record clinical outcomes, patient-specific factors, and treatment-related factors to improve patient selection and treatment strategies. By analyzing the relationship between radiation dose, technique, and timing with CAR-T therapy, the study seeks to optimize clinical outcomes and minimize treatment toxicity. Patient medical records and imaging data will be reviewed to assess disease progression and survival rates.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older
* Treatment with or intention to treat with radiation therapy, standard-of-care CAR-T cell therapy and/or standard-of-care bispecific therapy, within a 90 day window for a hematologic malignancy

Where it's running

• M D Anderson Cancer Center
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Penny Q Fang — M.D. Anderson Cancer Center
• Study coordinator: Penny Q Fang, MD
• Email: pfang@mdanderson.org
• Phone: 713-563-2345

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.