Osteopathic treatment for infants with low muscle tone

Comparison of Osteopathic Treatment Versus Simulation on Motor Development of Hypotonic Infants.

Not applicable Interventional Centre Hospitalier Intercommunal Creteil · NCT03852004

This study tests if osteopathic treatment can help improve muscle tone and motor skills in infants aged 8 to 24 months who have low muscle tone.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages8 Months to 24 Months
SexAll
SponsorCentre Hospitalier Intercommunal Creteil Academic / other
Locations2 sites (Créteil and 1 other locations)
Trial IDNCT03852004 on ClinicalTrials.gov

What this trial studies

This interventional study evaluates the effects of osteopathic treatment on the axial tone of hypotonic infants aged 8 to 24 months. Children referred to the 'Center Broussais' clinic for hypotonia will be assessed by a pediatrician and randomized into either an osteopathy group or a simulation group. The study involves three consultations where a neurological evaluation will be conducted to measure changes in motor development. If a child is in the simulation group, they will receive osteopathic treatment after the study concludes.

Who should consider this trial

Good fit: Ideal candidates are infants aged 8 to 24 months with axial hypotonia as determined by a pediatric neurological examination.

Not a fit: Patients with neuromuscular diseases that do not present with axial hypotonia or those with acute medical conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve motor development outcomes for hypotonic infants through targeted osteopathic interventions.

How similar studies have performed: While there is limited data on the effectiveness of osteopathy for hypotonia, similar studies in pediatric care have shown promising results with osteopathic interventions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:Age: 8 months-24 months corrected age Axial hypotonia in the neurological examination

* Age (age corrected for prematurity) of motor development evaluated on the Denver II scale below chronological age
* Proposal for osteopathic treatment by the pediatrician or treating physician

Exclusion Criteria:

* • Fever, shock or recent fall (face, skull, spine) not medically investigated, persistent cyanosis, bulging or depressed fontanel, cervical stiffness, fever

  * Neuromuscular diseases without axial hypotonia
  * Not affiliated to a social security scheme
  * Refusal to participate in the study by parents

Where this trial is running

Créteil and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hypotoniaosteopathyhypotoniachildren
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.