Osteopathic treatment for infants with head shape issues

OPT-IN: Osteopathic Plagiocephaly Treatment for Infants and Neonates

Not applicable Interventional Osteopathy's Promise to Children · NCT05848895

This study is testing if a special hands-on treatment can help babies with flat head syndrome get better results than just using regular repositioning methods.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment122 (estimated)
Ages1 Day to 4 Months
SexAll
SponsorOsteopathy's Promise to Children Academic / other
Locations1 site (San Diego, California)
Trial IDNCT05848895 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of osteopathic manipulative treatment (OMT) compared to standard repositioning care in infants diagnosed with positional plagiocephaly. Infants under 4 months of age will be randomly assigned to receive either OMT or standard care for 8 weeks, after which they will switch groups. The primary outcome is to measure improvements in cranial symmetry through anthropometric assessments. The study will involve a total of 122 participants.

Who should consider this trial

Good fit: Ideal candidates are infants under 4 months of age diagnosed with positional plagiocephaly.

Not a fit: Patients with preterm birth, genetic syndromes, or craniofacial defects will not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could provide a more effective non-invasive option for correcting cranial asymmetry in infants.

How similar studies have performed: While there is limited data on the specific use of OMT for this condition, similar approaches in treating cranial deformities have shown promise.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusions:

* Diagnosed with positional plagiocephaly
* Under 4-months of age (between birth - 4 months) at the time of enrollment

Exclusions:

* Preterm birth (\<37 weeks)
* Genetic syndromes
* Craniofacial defects/deformities (e.g. cleft lip/palate)
* Brachycephaly/scaphocephaly
* Hypotonia
* Hypertonia
* Craniosynostosis
* Head trauma or other neurological illnesses
* Lost to follow up
* Patient whose parents (or legal guardians) disagree to attend 8-treatments of OMT and 2 additional measurement sessions
* Prior helmet therapy, physical therapy, or OMT before the date of enrollment

Where this trial is running

San Diego, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Plagiocephaly, NonsynostoticPlagiocephaly, PositionalPlagiocephalyCraniumDeformityPositional PlagiocephalyNonsynostotic PlagiocephalyRepositioning
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.