Osteopathic treatment for head injuries in MMA fighters

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of osteopathic manipulative medicine (OMM) on recovery from head injuries sustained during mixed martial arts (MMA) fights. It aims to determine whether OMM can improve symptoms and cognitive recovery after a concussion by restoring alignment and releasing tension in the body. Participants will undergo OMM treatment or a sham intervention, and their cognitive performance will be assessed through online tests. The study builds on previous findings that OMM may enhance recovery in athletes with head injuries.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Part 1-head injury dynamics:

  1. individuals participating in MMA fights or sparring matches,
  2. 18 to 50 years of age,
  3. able to complete online cognitive neuropsychology tests.

     Part-2-Intervention:

  <!-- -->

  1. having a witnessed closed head injury during a fight

     Exclusion Criteria:
* Part 1-head injury dynamics:

  1. having a current or previous spinal cord injury,
  2. head injury within past six months,
  3. being unable to complete the assessment,
  4. been diagnosed with underlying neurodegenerative condition,
  5. pre-existing hypopituitary function,
  6. Pregnancy.

Part-2-Intervention:

1. has absolute contraindications to OMM (e.g. skull fracture, cervical spine fracture, signs of intracranial bleeding or increased intracranial pressure, cervical dissection, space occupying lesion in the cranium, or stroke),
2. suffered a witnessed loss of consciousness (LOC) for greater than 2 minutes, seizures, intractable vomiting or paralysis at the time of the head injury, Participants won't be referred to their private doctors for additional pituitary hormone testing unless there are clinical signs. The optional referral for growth hormone and other pituitary testing by glucagon stimulation Test at Quest labs will be contraindicated if there is risk of and/or a history of (1) cardiovascular (heart) disease, (2) disease of the blood vessel in your brain, or (3) seizures.

Where it's running

• Academic Health Care Center of NYIT College of Osteopathic Medicine
  Greenvale, New York, United States Recruiting

Study contacts

• Principal investigator: Jayme Mancini, D.O., Ph.D, FAWM — New York Institute of Technology College of Osteopathic Medicine, Academic Health Care Center, Riland Building
• Study coordinator: Milan Toma, Ph.D, SMIEEE
• Email: tomamil@tomamil.com
• Phone: 516-686-3799

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Biomarkers plus guidelines to reduce unnecessary brain CTs after head injury

  This trial tests whether adding GFAP and UCH-L1 biomarker results to standard guidelines can safely reduce head CT scans in adults with suspected traumatic brain injury who come to the emergency department.

  Recruiting at 6 sites University of Michigan · Sylmar, California and 5 other locations · NCT07829107

• Treatment and outcomes after mild head injury

  Researchers are looking at past emergency department records to see how often adults with mild head injury develop serious complications and whether the Canadian CT Head Rule or the NEXUS Head CT better predicts who will need surgery or die.

  Recruiting Azienda USL Reggio Emilia - IRCCS · Bologna and 3 other locations · NCT07339319

• Assessing mental health risks in adolescents with mild traumatic brain injury

  This study is trying to create a tool that helps doctors predict which teens aged 11 to 17 who have had a mild brain injury might develop new or worsening mental health issues.

  Recruiting at 6 sites University of California, Davis · Sacramento, California and 5 other locations · NCT06370520

• Evaluating the necessity of CT-scans for head injury patients on platelet inhibitors

  This study is testing if patients with minor head injuries who are on blood-thinning medications really need a CT-scan to check for bleeding in the brain.

  Recruiting at 10 sites Rennes University Hospital · Angers and 11 other locations · NCT03687528

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.