Osteopathic manual therapy versus ganglion impar block to treat chronic coccyx pain
Comparison of Osteopathic Manual Therapy and Ganglion Impar Block in Patients With Chronic Coccydynia
This trial will test whether osteopathic manual therapy or a ganglion impar block reduces pain and improves function in adults with chronic coccyx (coccydynia) pain.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Istanbul Medeniyet University Academic / other |
| Locations | 1 site (Istanbul, Sisli) |
| Trial ID | NCT07426497 on ClinicalTrials.gov |
What this trial studies
This randomized controlled trial will assign adults with chronic coccydynia to receive either a standardized program of osteopathic manual therapy or a fluoroscopy‑guided ganglion impar block. Pain intensity (Numeric Rating Scale) and functional disability (Oswestry Disability Index) will be measured at baseline, week 3, and month 3. Treatments are delivered at Medicana Zincirlikuyu Hospital and participants are followed for short‑term outcomes at three months. Eligible participants are 18–75 years old with at least three months of coccyx pain, moderate baseline pain and disability, and no contraindicating imaging or medical conditions.
Who should consider this trial
Good fit: Adults aged 18–75 with chronic coccygodynia for at least three months, baseline pain of NRS ≥4 and ODI ≥20, who have failed prior conservative treatments and have no fracture, infection, or malignancy on imaging are ideal candidates.
Not a fit: Patients with acute coccyx pain, prior spinal or coccygeal surgery, pelvic fracture, malignancy, pregnancy, coagulation disorders, severe psychiatric disease, or prior receipt of either osteopathic manual therapy or ganglion impar block are unlikely to benefit from enrollment.
Why it matters
Potential benefit: If successful, the results could identify which of the two treatments more reliably reduces coccyx pain and improves daily function for people with chronic coccydynia.
How similar studies have performed: Both manual therapy techniques and ganglion impar blocks have reported benefit in case series and small trials, but direct randomized comparisons are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18-75 years * Chronic coccygodynia ≥3 months * Baseline NRS ≥4 * ODI ≥20 * Failure of prior conservative treatment * Imaging excludes fracture, infection, or malignancy * Ability to provide written informed consent Exclusion Criteria: * Acute coccygodynia * Prior spinal or coccygeal surgery * Malignancy * Pelvic fracture * Pregnancy * Coagulation disorder * Severe psychiatric disease * Prior osteopathic manual therapy or ganglion impar block
Where this trial is running
Istanbul, Sisli
- Medicana Zincirlikuyu Hospital — Istanbul, Sisli, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: mert sancar, MD
- Email: mrtsncr88@gmail.com
- Phone: 5076367611
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.