OrthoApnea NOA custom mouthpiece for obstructive sleep apnea

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cohort follows people using the OrthoApnea NOA appliance over three years and compares their outcomes to archived data from patients who used other nylon-based mandibular advancement devices. The main goal is a reduction in the Apnea-Hypopnea Index (AHI) of at least 50% and, where possible, an AHI below 5 events per hour. The study also tracks device durability, long-term adherence, patient comfort, and whether brief morning use of a Morning Aligner helps reposition the jaw and reduce side effects. All enrollment and follow-up occur at the University of Alberta, with clinical measures taken at baseline and scheduled intervals through the follow-up period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Dxed OSA being treated with NOA appliance

Exclusion Criteria:

* no OSA Dx

Where it's running

• University of Alberta
  Edmonton, Alberta, Canada Recruiting

Study contacts

• Study coordinator: Primary Investigator
• Email: airwayresearchdsm@gmail.com
• Phone: (780) 492-7696

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Multimodal Deep Learning to Predict Sleep Apnea Severity from SpO2 and Ballistocardiography

  Researchers are testing a smart-mattress-based method that uses SpO2 and ballistocardiography data to predict sleep apnea severity in adults undergoing overnight sleep study.

  Recruiting Fu Jen Catholic University · New Taipei City, New Taipei City · NCT07923825

• Nightly wearable monitoring with at-home submental electrical stimulation for sleep apnea

  This pilot test checks whether wearing a ring sensor at night and doing a 4-week at-home submental electrical stimulation is feasible for adults with obstructive sleep apnea and looks at changes in sleep metrics.

  Recruiting E-DA Hospital · Kaohsiung City · NCT07921329

• Functional capacity and muscle function in adults with obstructive sleep apnea

  This study tests how obstructive sleep apnea affects respiratory and peripheral muscle strength, endurance, and upper‑extremity function compared with healthy adults.

  Recruiting Karabuk University · Karabük · NCT07913139

• Transcutaneous Electrical Stimulation for Obstructive Sleep Apnea

  This study tests whether applying gentle electrical stimulation to the throat muscles at night can reduce sleep apnea severity in adults with obstructive sleep apnea.

  Recruiting Mansoura University · Al Mansurah, Dakahlia Governorate · NCT07891702

• Physical activity habits and sleep/ breathing in obstructive sleep apnea

  This study tests whether daily physical activity habits affect sleep quality and breathing measurements in people with obstructive sleep apnea who are on CPAP therapy.

  Recruiting Medipol University · Istanbul, Göztepe · NCT07889154

• CES-EES score and a wearable ring for diagnosing obstructive sleep apnea

  This study tests whether the CES-EES clinical score and the Belun Ring wearable can accurately diagnose obstructive sleep apnea without in-lab polysomnography in adults referred for suspected OSA.

  Recruiting University of Malaya · Pantai Valley, Kuala Lumpur · NCT07785999

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.