ORN252 in healthy adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This Phase 1 interventional study enrolls healthy adult volunteers who will receive ORN252 and be monitored for safety and tolerability. Participants will undergo screening with medical history, physical exam, and laboratory tests, receive dosing per protocol at a single site, and return for scheduled follow-up visits where vital signs, labs, and adverse events are recorded. People with significant organ dysfunction or recent use of another investigational product are excluded. The study is sponsored by Orna Therapeutics and conducted at the Nucleus Network clinic in Herston, Queensland.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male and female participants who are healthy as determined by the Investigator based on review of medical history, physical examination, and laboratory tests
* Participant is willing and able to comply with study visits and other protocol requirements
* Other protocol specific inclusion criteria may apply

Exclusion Criteria:

* Clinically significant history or presence of organ dysfunction
* Use of any investigational product within 3 months, or 5 half-lives, whichever longer
* Other protocol specific exclusion criteria may apply

Where it's running

• Nucleus Network
  Herston, Queensland, Australia Recruiting

Study contacts

• Study coordinator: Orna Clinical Trials
• Email: ClinicalTrials@ornatx.com
• Phone: 877-728-6762

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Improved method to measure bone blood flow with total-body PET/CT in healthy adults

  This study tests whether a whole-body PET/CT scan using a safe radioactive tracer can measure bone blood flow in healthy volunteers aged over 50.

  Recruiting King's College London · London · NCT07860346

• ABS-201 for improving hair growth in healthy adults and people with androgenetic alopecia

  This trial will test whether ABS-201 is safe and helps hair grow in healthy adults and in men and women with androgenetic alopecia.

  Recruiting at 5 sites Phase 1/2 Absci Pty Ltd. · Sydney, New South Wales and 4 other locations · NCT07317544

• Effects of Exercise Snacks on Muscle Size and Strength in Healthy Young Adults

  This study tests whether many small workouts throughout the week can build muscle size and improve strength in healthy, untrained young adults compared with the usual twice-weekly workouts.

  Recruiting University of British Columbia · Vancouver, British Columbia · NCT07760597

• ORX489 safety and dosing in healthy adults ages 18 to 60

  This will test whether ORX489 tablets are safe, well tolerated, and how they are processed in the body in healthy men and women aged 18 to 60.

  Recruiting Phase 1 Centessa Pharmaceuticals (UK) Limited · Lincoln, Nebraska · NCT07413666

• ReHIIT Prehabilitation in Healthy Adults

  This pilot tests a combined resistance and high‑intensity interval training program to establish baseline physiology in healthy adults before applying findings to cancer patients.

  Recruiting University of Nottingham · Derby, Derbyshire · NCT07313332

• Safety and drug levels of a 3‑month naltrexone implant (BICX104) with or without bupropion versus monthly Vivitrol injections

  This will test whether a three‑month naltrexone implant (BICX104), given alone or with extended‑release bupropion, is safe and keeps steady drug levels compared with monthly Vivitrol injections in healthy adults.

  Recruiting Phase 1 BioCorRx Pharmaceuticals Inc · Miami, Florida · NCT07269873

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.