Oral oxytocin and atosiban effects on social attention in healthy men

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a double-blind, placebo-controlled, between-subject experiment in healthy male volunteers testing two doses of lingual (sublingual/supragingival) oxytocin (24 IU and 48 IU) with and without the oxytocin receptor antagonist atosiban. Participants complete baseline questionnaires and provide repeated blood and saliva samples across three sequential medication administrations. After dosing and a monitored waiting period, participants perform four eye-tracking visual attention tasks: dynamic social versus geometric stimuli, gaze-following, face emotion processing, and empathy for naturalistic scenes. Behavioral outcomes will be compared across dose and task conditions and related to biological measures to determine oxytocin receptor–mediated effects.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Healthy male subjects without past or current psychiatric or neurological disorders

Exclusion Criteria:

* History of or current neurological/psychiatric disorders;
* Use of psychotropic medications (including nicotine)
* Visual impairments

Where it's running

• School of Life science and Technology, University of Electronic Science and Technology of China
  Chengdu, Sichuan, China Recruiting

Study contacts

• Study coordinator: Keith M Kendrick, PhD
• Email: k.kendrick.uestc@gmail.com
• Phone: 86-28-61830811

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.