Oral oxytocin and atosiban effects on attention control

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a double-blind, placebo-controlled, between-subject early-phase experiment in healthy male volunteers comparing two doses of lingual oxytocin (24 IU and 48 IU), atosiban, and placebo. Participants complete baseline questionnaires, provide blood and saliva samples, receive timed sublingual/supragingival medication administrations, and then complete an antisaccade eye-tracking task while researchers record latency, error rate, and pupil size. Samples are taken before and after dosing to link peripheral markers with behavioral effects, and state anxiety is measured before and after the behavioral paradigm. The design tests dose- and task-dependence and whether effects are mediated via oxytocin receptors using the antagonist atosiban.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Healthy male subjects without past or current psychiatric or neurological disorders

Exclusion Criteria:

* History of or current neurological/psychiatric disorders;
* Use of psychotropic medications (including nicotine)
* Visual impairments

Where it's running

• School of Life science and Technology, University of Electronic Science and Technology of China
  Chengdu, Sichuan, China Recruiting

Study contacts

• Study coordinator: Keith M Kendrick, PhD
• Email: k.kendrick.uestc@gmail.com
• Phone: +86-28-61830811

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.