Oral gabapentin versus diclofenac for pain after laparoscopic gallbladder removal
Comparative Study Between the Efficacy of Pre- Operative Oral Gabapentin Versus Diclofenac Sodium in Post-operative Analgesia in Adult Undergoing Laparoscopic Cholecystectomy
This trial will test whether taking oral gabapentin or diclofenac around the time of surgery better controls pain after laparoscopic cholecystectomy in adults aged 20–60.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 20 Years to 60 Years |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Trial ID | NCT07131527 on ClinicalTrials.gov |
What this trial studies
This interventional, single-center comparison gives perioperative oral gabapentin to one group and oral diclofenac sodium to another in patients undergoing laparoscopic cholecystectomy, with postoperative pain and analgesic use recorded. Eligible participants are adults 20–60 years old with ASA physical status I–II, while patients with hypertension, pregnancy, BMI >35 kg/m2, diabetes, alcoholism, or who refuse are excluded. Interventions are administered around the time of surgery and outcomes typically include pain scores and need for rescue analgesia in the immediate postoperative period. The work is conducted at Sohag University Hospital and aims to identify which medication provides better postoperative analgesia for this procedure.
Who should consider this trial
Good fit: Adults aged 20–60 of either sex with ASA I–II who are scheduled for laparoscopic cholecystectomy and do not have hypertension, diabetes, pregnancy, morbid obesity (BMI >35), or alcohol dependence.
Not a fit: Patients with hypertension, diabetes, pregnancy, BMI >35, alcohol dependence, or those outside the 20–60 age range are excluded and unlikely to benefit from the study's findings.
Why it matters
Potential benefit: If successful, the preferred drug could reduce postoperative pain and lower the need for stronger opioid painkillers after laparoscopic gallbladder surgery.
How similar studies have performed: Previous studies have shown that gabapentin and NSAIDs like diclofenac can each reduce postoperative pain and opioid use in some settings, though results vary by surgery type and dosing.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Age from 20 to 60 years old. Both sexes. American Society of Anesthesiologists (ASA) physical status I- II. Patients undergoing laparoscopic cholecystectomy. Exclusion Criteria: Patients with hypertension. Pregnant women. Obese patients with BMI \>35 kg/m2. Alcoholics. Patients With DM Patient refusal
Where this trial is running
Sohag
- Sohag university hospital — Sohag, Egypt (Recruiting)
Study contacts
- Study coordinator: Manar Z Ismaiel, Resident
- Email: manorzakaria90@gmail.com
- Phone: 01027233046
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.