Optimizing treatment for adhesive small bowel obstruction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to improve the treatment protocols for adhesive small bowel obstruction (aSBO), a common gastrointestinal issue. It will assess the feasibility of randomizing patients to receive either nasogastric tubes (NGTs) or water-soluble contrast (WSC) as part of their treatment. The study will also focus on measuring health-related quality of life (HRQOL) as a primary outcome, addressing critical gaps in understanding who benefits from NGT placement and how to manage feeding reintroduction. The trial will involve patients aged 18 and older who exhibit clinical features of aSBO.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Male or female ≥18 years of age.
2. Documentation of aSBO as evidenced by one or more clinical features meeting the following criteria: Nausea, emesis, abdominal pain, distended abdomen CT evidence of aSBO

Exclusion Criteria:

1. Pregnant, breastfeeding, or unwilling to practice birth control during participation in the study.
2. Presence of a condition or abnormality that in the opinion of the investigator would compromise the safety of the patient or the quality of the data.
3. Unstable angina or recent myocardial infarction (MI)/stroke within 6 months
4. Nonadhesive SBO

   1. Paralytic Ileus
   2. Incarcerated hernia
   3. Fecal impaction
   4. Intra-abdominal malignancy Early aSBO within 4 weeks of a prior abdominal operation

Where it's running

• University of California, Los Angeles, David Geffen School of Medicine
  Los Angeles, California, United States Recruiting

Study contacts

• Study coordinator: Steven Stokes
• Email: sstokes@mednet.ucla.edu
• Phone: 310-206-7436

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.