Optimizing strategies to boost cervical cancer prevention in Malawi
Kupewa: Optimizing Implementation Strategies for Cervical Cancer Prevention
This project tests whether training, coaching, and reminder systems for health workers can increase provider recommendation and uptake of cervical cancer prevention tools among adolescents and young women receiving HIV care in Malawi.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 7000 (estimated) |
| Ages | 9 Years and up |
| Sex | All |
| Sponsor | New York University Academic / other |
| Locations | 1 site (Lilongwe) |
| Trial ID | NCT07015957 on ClinicalTrials.gov |
What this trial studies
This implementation trial will deliver a package of strategies — in-person and virtual training, one-on-one coaching, and prompts/reminders — to health workers at participating clinics in Lilongwe, Malawi. Researchers will measure changes in provider recommendation rates and client uptake of cervical cancer prevention tools among non-pregnant females aged 9–24 receiving HIV care. They will also collect data on acceptability, appropriateness, feasibility, cost, and the durability of any improvements over time. Results will inform which combination of strategies is most implementable and scalable in similar low-resource HIV care settings.
Who should consider this trial
Good fit: Ideal participants are clinical officers, nurses, and medical assistants who regularly provide HIV care at participating facilities and non-pregnant female clients aged 9–24 (with parental consent for those under 18).
Not a fit: People who are pregnant, younger than 9 or older than 24, not receiving HIV care at the participating clinics, or attending non-participating facilities are unlikely to benefit from this program.
Why it matters
Potential benefit: If successful, these strategies could increase how often health workers recommend and deliver cervical cancer prevention services to adolescents and young women with HIV, reducing future cancer risk.
How similar studies have performed: Similar combinations of training, coaching, and reminder systems have improved provider behaviors and preventive service uptake in other low-resource settings, but the best mix of strategies for cervical cancer prevention in HIV care remains unconfirmed.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Health workers: People who provide medical care and counseling (typically medical assistants, clinical officers, and nurses), and interact with adolescent girls and young women aged 9-24 and/or their parents/caregivers. * Clients: Non-pregnant females aged 9-24 (for those aged 9-17, their male or female parent/guardian will also be eligible for participation) who present for HIV care at a participating health facility during the study period. Exclusion Criteria: * Health workers: Less than 18 years of age, or not an active and regular provider of medical care or counseling at the facility, or unable or unwilling to provide informed consent. * Clients: \<9 or \>24 years old, or pregnancy, or unable or unwilling to provide informed consent.
Where this trial is running
Lilongwe
- Partners in Hope — Lilongwe, Malawi (Recruiting)
Study contacts
- Principal investigator: Corrina Moucheraud — New York University
- Study coordinator: Corrina Moucheraud
- Email: c.moucheraud@nyu.edu
- Phone: 212-992-6129
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.