Optimizing PPI prescribing with EHR decision support
Quality Improvement Initiative Leveraging Electronic Healthcare Records to Reduce Inappropriate Proton Pump Inhibitors (PPI) Prescribing at UCLA.
NA · University of California, Los Angeles · NCT06998966
This project tests whether changing EHR prescription defaults and adding active-choice prompts will reduce overprescribing of proton pump inhibitors by UCLA primary care physicians.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 372 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | University of California, Los Angeles (other) |
| Locations | 1 site (Los Angeles, California) |
| Trial ID | NCT06998966 on ClinicalTrials.gov |
What this trial studies
The initiative implements alternative order-panel configurations in UCLA's CareConnect EHR, including indication-based default durations and active physician-choice prompts, to influence PPI prescribing workflows. Changes are embedded in routine practice so clinicians retain full authority to modify prescriptions. The study compares prescribing patterns across the different EHR configurations to see if defaults change behavior while monitoring for safety and workflow impact. Eligible participants are UCLA primary care physicians with at least 25% clinical full-time equivalency.
Who should consider this trial
Good fit: Primary care physicians at UCLA Health with a clinical full-time equivalency of at least 25% are the intended participants.
Not a fit: Patients with clear indications for long-term PPI therapy (for example, Barrett's esophagus, high-risk GI bleeding history, or other specialist-directed chronic use) may not experience reduced prescriptions from default changes.
Why it matters
Potential benefit: If successful, this could reduce unnecessary long-term PPI use and lower patients' medication exposure and related risks.
How similar studies have performed: Previous EHR default and nudging interventions have reduced inappropriate prescribing in other settings, although effectiveness varies by context and design.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * UCLA Health primary care physicians who have a clinical full-time equivalency of at least 25%. Exclusion Criteria: * Physicians with a clinical full-time equivalency of less than 25%
Where this trial is running
Los Angeles, California
- UCLA Health System — Los Angeles, California, United States (RECRUITING)
Study contacts
- Study coordinator: Katelyn Clinical Research Coordinator
- Email: katenguyen@mednet.ucla.edu
- Phone: 310-267-5250
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Prescribing Patterns, Physician, Physician', s Practice Patterns, Drug Utilization Review, Proton Pump Inhibitors, Quality Improvement, Healthcare Utilization, Clinical Decision Support