Optimizing indocyanine green dose and storage for sentinel lymph node mapping in gynecologic cancers
The Effect of Dose and Storage Conditions of Indocyanine Green on Efficacy and Cost in Sentinel Lymph Node Mapping in Gynecological Cancer
Cukurova University · NCT07380698
This project will test whether changing the dose and storage conditions of indocyanine green improves sentinel lymph node mapping for people with endometrial, cervical, or vulvar cancer.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Sex | Female |
| Sponsor | Cukurova University (other) |
| Locations | 1 site (Adana) |
| Trial ID | NCT07380698 on ClinicalTrials.gov |
What this trial studies
This observational study will follow patients with endometrial, cervical, or vulvar cancer who undergo sentinel lymph node (SLN) mapping using indocyanine green (ICG) to compare different ICG doses and storage conditions. Investigators will record SLN detection rates, bilateral mapping success, and ultrastaging results to capture micrometastasis detection. The study will also collect cost and supply data to model potential savings from optimized dosing and storage practices. All participants receive standard surgical care at the study site while additional data are collected non‑interventionally.
Who should consider this trial
Good fit: Ideal candidates are people with endometrial, cervical, or vulvar cancer who are planned for sentinel lymph node dissection using indocyanine green.
Not a fit: Patients who are not undergoing SLN mapping, who have a known allergy to ICG, or whose disease requires a full lymphadenectomy may not benefit from this work.
Why it matters
Potential benefit: If successful, optimized ICG dosing and storage could increase detection of micrometastases during SLN mapping and reduce procedure costs.
How similar studies have performed: ICG-guided SLN mapping is already well supported by prior studies in gynecologic cancers, but systematic optimization of dose and storage conditions is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * cervical cancer, endometrial cancer, vulvar cancer, using indocyanine green, sentinel lymph node dissection Exclusion Criteria: \-
Where this trial is running
Adana
- Cukurova University — Adana, Turkey (Türkiye) (RECRUITING)
Study contacts
- Study coordinator: Ghanim Khatib, MD
- Email: ghanim.khatib@gmail.com
- Phone: +903223386060
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Endometrial Cancer, Vulvar Cancers, Cervical Cancer, Indocyanine Green, endometrial cancer, vulvar cancers, cervical cancers