Optimizing indocyanine green dose and storage for sentinel lymph node mapping in gynecologic cancers
Official title: The Effect of Dose and Storage Conditions of Indocyanine Green on Efficacy and Cost in Sentinel Lymph Node Mapping in Gynecological Cancer
Run by Cukurova University · NCT07380698 · Data updated 2026-11-12
This project will test whether changing the dose and storage conditions of indocyanine green improves sentinel lymph node mapping for people with endometrial, cervical, or vulvar cancer.
Quick facts
| Study type | Observational |
|---|---|
| Sex | Women only |
| Enrollment | 30 (estimated) |
| Sponsor | Cukurova University Academic / other |
| Locations | 1 site (Adana) |
| Status | Recruiting |
| Started | October 3, 2025 |
| Main results expected | August 3, 2026 |
| Study ends | September 3, 2026 |
| Registry record updated | February 2, 2026 |
| Trial ID | NCT07380698 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are people with endometrial, cervical, or vulvar cancer who are planned for sentinel lymph node dissection using indocyanine green.
✕Probably not a fit
Patients who are not undergoing SLN mapping, who have a known allergy to ICG, or whose disease requires a full lymphadenectomy may not benefit from this work.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study will follow patients with endometrial, cervical, or vulvar cancer who undergo sentinel lymph node (SLN) mapping using indocyanine green (ICG) to compare different ICG doses and storage conditions. Investigators will record SLN detection rates, bilateral mapping success, and ultrastaging results to capture micrometastasis detection. The study will also collect cost and supply data to model potential savings from optimized dosing and storage practices. All participants receive standard surgical care at the study site while additional data are collected non‑interventionally.
Why it matters
Potential benefit: If successful, optimized ICG dosing and storage could increase detection of micrometastases during SLN mapping and reduce procedure costs.
How similar studies have gone: ICG-guided SLN mapping is already well supported by prior studies in gynecologic cancers, but systematic optimization of dose and storage conditions is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * cervical cancer, endometrial cancer, vulvar cancer, using indocyanine green, sentinel lymph node dissection Exclusion Criteria: \-
Where it's running
-
Cukurova University
Adana, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Ghanim Khatib, MD
- Email: ghanim.khatib@gmail.com
- Phone: +903223386060
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.