Optimizing fluid management during brain surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enhance fluid management during brain surgery by comparing two methods of hemodynamic monitoring: invasive measurements using pulse pressure variation (PPV) and systolic pressure variation (SPV) versus noninvasive measurements using the ClearSight system. The goal is to reduce perioperative risks and improve patient outcomes by ensuring adequate fluid management based on the most effective monitoring technique. Participants will be assigned to either the invasive or noninvasive group to evaluate the effectiveness of each approach in optimizing fluid responsiveness.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Glasgow Coma scale 15
* ASA Physical Status Classification System I-III
* planed surgery for brain tumor to 5 hours
* postoperative awakening
* sinus rhythm

Exclusion Criteria:

* NYHA III, IV
* BMI over 40 in females and over 35 in men
* awake operation
* postoperative artificial ventilation

Where it's running

• University Hospital Hradec Kralove
  Hradec Králové, Czechia Recruiting

Study contacts

• Study coordinator: Vlasta Dostálová, MD, Ph.D.
• Email: dostavla@seznam.cz
• Phone: 777883571

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.