Optimizing breathing support during robotic prostate surgery
Application of Individualized Positive End-expiratory Pressure Using Electrical Impedance Tomography (EIT) in Patients Undergoing Robot Assisted Laparoscopic Prostatectomy : a Randomized Controlled Study
NA · Gangnam Severance Hospital · NCT05669443
This study is testing whether using a personalized breathing support during robotic prostate surgery can improve how well patients breathe while under anesthesia.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 42 (estimated) |
| Ages | 20 Years to 70 Years |
| Sex | Male |
| Sponsor | Gangnam Severance Hospital (other) |
| Locations | 1 site (Seoul) |
| Trial ID | NCT05669443 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of individualized positive end-expiratory pressure (PEEP) on ventilation during robot-assisted laparoscopic prostatectomy. Patients will be assigned to receive either a conventional PEEP of 5 cmH2O or a personalized PEEP value determined through electrical impedance tomography. The primary goal is to assess intraoperative ventilation efficiency by analyzing arterial blood gas levels, aiming to enhance patient outcomes during surgery.
Who should consider this trial
Good fit: Ideal candidates are adults aged 20 to 70 scheduled for robotic assisted laparoscopic prostatectomy with an ASA-PS classification of I-III and a BMI of 35 kg/m2 or less.
Not a fit: Patients with pre-existing lung diseases, a BMI over 35 kg/m2, or those unable to tolerate positive end-expiratory pressure will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved ventilation management during robotic prostate surgeries, potentially enhancing patient safety and recovery.
How similar studies have performed: While the specific approach of individualized PEEP is novel, similar studies have shown that optimizing ventilation strategies can improve surgical outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. 20 - 70 years of age who are scheduled for robotic assisted laparoscopic prostatectomy at the Department of Urology, Gangnam Severance Hospital, 2. ASA-PS (American Society of Anesthesiology Body Rating) I-IlI, 3. Patients with a BMI of 35 kg/m2 or less Exclusion Criteria: 1. Patients with lung disease 2. BMI \>35kg/m2 3. Patients for whom positive end-tidal pressure cannot be applied (large bullae, severe cardiac disease) 4. patient refusal
Where this trial is running
Seoul
- Gangnam Severacne Hospital Yonsei University College of Medicine — Seoul, Korea, Republic of (RECRUITING)
Study contacts
- Study coordinator: Chul-Ho Chang
- Email: ANEZZANG@yuhs.ac
- Phone: 82-2-2019-4601
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Prostate Cancer