Optimizing assessment strategies for carotid artery stenosis
Cohort of Optimized Assessment Strategy of Carotid Artery Stenosis
This study is testing different imaging methods to see which ones work best for checking carotid artery blockages and their effects on the brain in people undergoing surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Peking Union Medical College Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Trial ID | NCT05629000 on ClinicalTrials.gov |
What this trial studies
This observational study aims to enhance the evaluation of carotid artery stenosis by utilizing multiple imaging techniques, including MRI, CT, and ultrasound. It focuses on identifying the best strategies for assessing cerebral lesions and perfusion, as well as the characteristics of carotid plaques. Participants will undergo imaging examinations before and after carotid revascularization surgery, with data on their basic characteristics, imaging results, and biological samples collected for analysis.
Who should consider this trial
Good fit: Ideal candidates are patients with severe carotid artery stenosis (≥50%) or near-occlusion who are scheduled for carotid endarterectomy.
Not a fit: Patients with contraindications to imaging examinations or those who refuse to sign informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and treatment strategies for patients with carotid artery stenosis.
How similar studies have performed: While similar approaches using multi-modal imaging have been explored, this specific optimization strategy is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. patients with severe stenosis (≥50%) or near-occlusion diagnosed by computed tomographic angiogram; 2. patients received carotid endarterectomy at Peking Union Medical College Hospital Exclusion Criteria: (1) Any contraindication to image examination; (3) refuse to sign the Informed consent.
Where this trial is running
Beijing, Beijing Municipality
- vascular surgery department of PUMCH — Beijing, Beijing Municipality, China (Recruiting)
Study contacts
- Study coordinator: Zhichao Lai, MD
- Email: zhichao_lai@126.com
- Phone: 01069152500
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.