Clinical trial Recruiting at 1 site Observational Ages 18 and up

Optimizing assessment strategies for carotid artery stenosis

Official title: Cohort of Optimized Assessment Strategy of Carotid Artery Stenosis

Run by Peking Union Medical College Hospital · NCT05629000 · Data updated 2026-11-12

This study is testing different imaging methods to see which ones work best for checking carotid artery blockages and their effects on the brain in people undergoing surgery.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorPeking Union Medical College Hospital
Academic / other
Locations1 site (Beijing, Beijing Municipality)
StatusRecruiting
StartedJanuary 1, 2015
Main results expectedDecember 31, 2025
Study endsDecember 31, 2026
Registry record updatedNovember 29, 2022
Trial IDNCT05629000 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients with severe carotid artery stenosis (≥50%) or near-occlusion who are scheduled for carotid endarterectomy.

Probably not a fit

Patients with contraindications to imaging examinations or those who refuse to sign informed consent may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to enhance the evaluation of carotid artery stenosis by utilizing multiple imaging techniques, including MRI, CT, and ultrasound. It focuses on identifying the best strategies for assessing cerebral lesions and perfusion, as well as the characteristics of carotid plaques. Participants will undergo imaging examinations before and after carotid revascularization surgery, with data on their basic characteristics, imaging results, and biological samples collected for analysis.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic and treatment strategies for patients with carotid artery stenosis.

How similar studies have gone: While similar approaches using multi-modal imaging have been explored, this specific optimization strategy is novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. patients with severe stenosis (≥50%) or near-occlusion diagnosed by computed tomographic angiogram;
2. patients received carotid endarterectomy at Peking Union Medical College Hospital

Exclusion Criteria:

(1) Any contraindication to image examination; (3) refuse to sign the Informed consent.

Where it's running

  • vascular surgery department of PUMCH
    Beijing, Beijing Municipality, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.