Optimizing anti-infective drug treatment for bone and joint infections
Model-informed Individualized Treatment of Anti-infective Drugs in Patients With Osteoarticular Infections
Shandong University · NCT06711562
This study is testing a personalized approach to treating bone and joint infections by adjusting anti-infective medications based on how each patient responds to them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Sex | All |
| Sponsor | Shandong University (other) |
| Locations | 1 site (Jinan) |
| Trial ID | NCT06711562 on ClinicalTrials.gov |
What this trial studies
This study focuses on improving the treatment of osteoarticular infections by personalizing anti-infective drug therapy. It utilizes population pharmacokinetics to analyze drug exposure in patients' blood and tissues, aiming to tailor treatments based on individual responses. By understanding how different patients metabolize these drugs, the study seeks to enhance therapeutic outcomes and minimize adverse effects.
Who should consider this trial
Good fit: Ideal candidates include patients with suspected or confirmed osteoarticular infections who are currently receiving anti-infective drug therapy.
Not a fit: Patients who are pregnant or lactating, or those with other unspecified factors deemed unsuitable by researchers, may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more effective and safer treatment options for patients with osteoarticular infections.
How similar studies have performed: While this approach is innovative, similar studies in personalized medicine have shown promise in optimizing drug therapies, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with suspected/confirmed osteoarticular infections who are undergoing anti-infective drug therapy. Exclusion Criteria: * Pregnant/lactating women. * There are other factors that the researchers think are not suitable for inclusion.
Where this trial is running
Jinan
- Shandong Public Health Clinical Center — Jinan, China (RECRUITING)
Study contacts
- Principal investigator: Wei Zhao, Ph.D — Shandong University
- Study coordinator: Wei Zhao, Ph.D
- Email: zhao4wei2@hotmail.com
- Phone: 86053188383308
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Osteoarticular Infections