Clinical trial Recruiting at 1 site Interventional Ages 14 and up

Optimizing anesthesia for pediatric Le Fort surgeries

Official title: Anesthetic Optimization in Pediatric LeFort Surgeries

Run by Johns Hopkins University · NCT05260320 · Data updated 2026-11-12

This study is testing a new anesthesia plan for kids having Le Fort surgeries to see if it helps them feel less pain afterward and recover faster compared to the usual care.

Quick facts

Study typeInterventional
Ages14 Years and up
SexAll
Enrollment50 (estimated)
SponsorJohns Hopkins University
Academic / other
Locations1 site (Baltimore, Maryland)
StatusRecruiting
StartedMay 2, 2025
Main results expectedFebruary 2027
Study endsJuly 2027
Registry record updatedMay 20, 2026
Trial IDNCT05260320 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are pediatric patients aged 14 years and older who are scheduled for Le Fort osteotomy at Johns Hopkins Hospital.

Probably not a fit

Patients with contraindications to the standardized anesthetic protocol will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates a standardized anesthetic protocol for pediatric patients undergoing Le Fort osteotomy at Johns Hopkins Hospital. It includes two cohorts: one receiving the new anesthesia protocol and a historical cohort that received standard care. The goal is to minimize postoperative pain, reduce hospital stays, and lower long-term complications. By comparing outcomes between the two groups, the study aims to demonstrate the benefits of a more structured anesthetic approach.

Why it matters

Potential benefit: If successful, this could lead to improved surgical outcomes and reduced postoperative complications for pediatric patients.

How similar studies have gone: Other studies have shown success with standardized anesthetic protocols in various surgical settings, suggesting potential for positive outcomes in this context.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Undergoing Le Fort osteotomy at Johns Hopkins Hospital
* Age \>= 14 years

Exclusion Criteria:

* Contraindications to standardized anesthetic protocol (intervention arm)

Where it's running

  • Johns Hopkins Hospital
    Baltimore, Maryland, United States
    Recruiting

Study contacts

  • Principal investigator: Robin Yang, MD, DDS — Johns Hopkins University
  • Study coordinator: Robin Yang, MD, DDS
  • Email: ryang14@jhmi.edu
  • Phone: 443-997-9466

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.