Opioid-free pain management for patients undergoing laparoscopic sleeve gastrectomy
Effect of Opioid-free Analgesia and Anesthesia on the Quality of Postoperative Recovery and Nausea Vomit in Patients Receiving Laparoscopic Sleeve Gastrectomy
This study is testing whether using non-opioid pain relief methods can help people recover better and feel less nausea after laparoscopic sleeve gastrectomy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 76 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Beijing Friendship Hospital Academic / other |
| Locations | 1 site (Beijing) |
| Trial ID | NCT06305221 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of opioid-free analgesia and anesthesia on postoperative recovery and nausea in patients undergoing laparoscopic sleeve gastrectomy. It aims to utilize alternative analgesics such as esketamine and dexmedetomidine to manage pain without the use of opioids. The approach focuses on minimizing the side effects associated with opioids, particularly in the context of postoperative recovery. The study will assess the quality of recovery and incidence of nausea and vomiting in participants receiving this novel pain management strategy.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-65 with a BMI over 30 who are scheduled for elective laparoscopic sleeve gastrectomy.
Not a fit: Patients with chronic pain, severe liver or renal dysfunction, or significant neurological disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved postoperative recovery and reduced nausea for patients undergoing laparoscopic sleeve gastrectomy.
How similar studies have performed: Other studies have shown promise in using opioid-free analgesia, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria:
* Patients undergoing elective laparoscopic sleeve gastrectomy
* ASAA I or grade;
* volunteered in this trial and signed informed consent; ④ age 18-65 years; ⑤ BMI\> 30kg / m2.
Exclusion Criteria:
* chronic pain;
* severe liver dysfunction (total bilirubin 2 mg dl-1);
* severe renal dysfunction (glomerular filtration rate 60ml min-1 1.73m-2);
* pregnancy or lactation;
* preoperative heart rate \<50 beats / min, sick sinus syndrome, severe heart block; -dementia or significant neurological disorders (such as stroke, epilepsy, intracranial tumors, PD, etc.);
* history of alcohol or drug abuse
Where this trial is running
Beijing
- bijia Song — Beijing, China (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.