Opioid-free anesthesia for lung cancer surgery
The Efficacy and Safety of Opioid-free Anesthesia(OFA) for Non-small-cell Lung Cancer Resection and Its Underlying Clinical Value: a Prospective Study
NA · Shanghai Zhongshan Hospital · NCT05063396
This study tests if using opioid-free anesthesia during lung cancer surgery can help patients recover better and avoid problems related to opioids.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Shanghai Zhongshan Hospital (other) |
| Locations | 2 sites (Shanghai and 1 other locations) |
| Trial ID | NCT05063396 on ClinicalTrials.gov |
What this trial studies
This study investigates the efficacy and safety of opioid-free anesthesia (OFA) for patients undergoing non-small-cell lung cancer resection. It compares OFA with opioid-sparing anesthesia (OSA) to evaluate their clinical value and impact on postoperative recovery. The approach utilizes a combination of hypnotics, local anesthetics, anti-inflammatory drugs, and other techniques to minimize opioid use during surgery. The goal is to reduce opioid-related adverse events and enhance recovery times for patients undergoing thoracoscopic lung surgery.
Who should consider this trial
Good fit: Ideal candidates are patients scheduled for thoracoscopic lung surgery who are ASA grade I-II and can effectively communicate pain levels.
Not a fit: Patients with psychological disorders or cognitive dysfunction may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce opioid-related complications and improve recovery outcomes for lung cancer surgery patients.
How similar studies have performed: Previous studies have shown that opioid-sparing and opioid-free anesthesia can reduce adverse events and improve recovery, but this specific comparison is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * going through thoracoscopic lung surgery including lobectomy, segmentectomy, single or multiple wedge resection, and two of the above procedures combined; * able to complete the pain scoring face-to-face; * no cognitive dysfunction or history of anesthetic drug allergy; * ASA grade I-II Exclusion Criteria: -psychological disorders
Where this trial is running
Shanghai and 1 other locations
- 180 Fenglin Road — Shanghai, China (RECRUITING)
- Zhongshan Hospital — Shanghai, China (RECRUITING)
Study contacts
- Study coordinator: SHUWEI WANG
- Email: veronicawang228@126.com
- Phone: +8613564440601
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Thoracic Cancer, opioid free anesthesia, non small cell lung caner