Online weight loss program for sexual minority women

Optimizing an Online Behavioral Weight Loss Intervention and Novel Culturally Tailored Components for Sexual Minority Women: MOST Optimization Phase

Not applicable Interventional The Miriam Hospital · NCT05775497

This study tests an online weight loss program designed specifically for sexual minority women to see if it can help them overcome unique challenges and lose weight effectively.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment88 (estimated)
Ages18 Years to 70 Years
SexFemale
SponsorThe Miriam Hospital Academic / other
Locations1 site (Providence, Rhode Island)
Trial IDNCT05775497 on ClinicalTrials.gov

What this trial studies

This intervention focuses on addressing obesity among sexual minority women through an online behavioral weight loss program. The program incorporates culturally tailored components that target specific barriers faced by this group, such as minority stress, low social support, and negative body image. The approach is designed to be effective, low-cost, and scalable, making it accessible to a wider audience. The study includes qualitative feedback from participants to enhance the program's relevance and usability.

Who should consider this trial

Good fit: Ideal candidates include sexual minority women aged 18-70 with a BMI between 25-50 who are interested in losing weight.

Not a fit: Patients with serious mental or physical health conditions that could increase treatment risks may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly improve weight loss outcomes and overall health for sexual minority women.

How similar studies have performed: Other studies have shown success with culturally tailored interventions for specific populations, suggesting potential for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
* Assigned female at birth and currently identify as female
* Self-identify a minority sexual orientation (e.g.,lesbian, bisexual)
* BMI=25-50kg/m2
* 18-70 years old
* Interested in losing weight
* Regular internet and e-mail access
* No significant weight loss within past 6 months (\>5%)
* Fluent in English
* Able to participate in moderate physical activity
* Not currently enrolled in a weight loss program
* Not currently taking weight-loss medication
* Not currently pregnant or trying to get pregnant
* Participated in a previous Phase of this study
* Reports a serious mental/physical health condition that would increase potential risks of treatment to the participant (e.g., active symptoms of psychosis, suicidality, mania, alcohol/substance use, or a medical condition that is serious, active, unstable, and degenerative (e.g., CHF)).

Where this trial is running

Providence, Rhode Island

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions ObesitySexual minority womenLGBTQ healthWeight loss
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.