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Clinical trial Recruiting at 1 site Interventional Ages 16 to 25

Online social therapy for young people on mental health waiting lists

Official title: ENgage YOung People earlY: the Next Steps

Run by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · NCT07594756 · Data updated 2026-11-12

This study tests whether the ENYOY online platform, plus usual care, can reduce psychological distress in 16- to 25-year-olds on a mental health waiting list.

Quick facts

Study typeInterventional
Ages16 Years to 25 Years
SexAll
Enrollment225 (estimated)
SponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Academic / other
Locations1 site (Amsterdam)
StatusRecruiting
StartedMay 18, 2026
Main results expectedDecember 31, 2028
Study endsDecember 31, 2028
Registry record updatedOctober 5, 2026
Trial IDNCT07594756 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Young people aged 16–25 on a waiting list for mental health care who have sufficient Dutch language skills and access to a digital device, and who consent to participate.

Probably not a fit

Patients without meaningful engagement with the online platform or those whose distress is primarily due to non-psychological factors may show limited benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Young people aged 16 to 25 with mental health difficulties who are waiting for care are randomized to receive either the ENYOY online platform with three months of guided support plus care as usual, or care as usual alone. The trial lasts 12 months, with questionnaires at baseline, 3, 6, and 12 months to track distress and other mental health outcomes. ENYOY offers personalized, self-guided therapeutic content and moderated peer support. The study aims to determine the cost-effectiveness and clinical impact of adding ENYOY to standard waiting-list care. No expected adverse health risks are anticipated beyond standard care considerations.

Why it matters

Potential benefit: If successful, participants may experience reduced psychological distress and improved mental health outcomes while waiting for care.

How similar studies have gone: Prior digital mental health interventions for youth have shown mixed but promising reductions in distress when combined with usual care.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Age 16-25 years
* On a waiting list for mental healthcare.
* Able and willing to consent.
* A score of 10 or higher on the CORE-10 questionnaire.
* Personal and private access to a computer, smartphone or tablet.
* Ability and willingness to nominate an emergency contact person, such as a close family member.

Exclusion Criteria:

* Insufficient command of the Dutch language.
* Present with acute suicidal behavior or imminent risk of harm to self.
* If their psychiatric symptoms are due to an organic cause.
* Prior exposure to ENYOY or MOST.

Where it's running

  • Amsterdam UMC
    Amsterdam, Netherlands     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.