Clinical trial Recruiting at 1 site Interventional Ages 18 to 66

Online resilience training program for people with Multiple Sclerosis to help prevent job loss

Official title: Assessing NHS ImplemeNTation of an onlinE Resilience Training Acceptance and Commitment Therapy (ACT) Programme to Prevent Job Loss in Multiple Sclerosis

Run by The Leeds Teaching Hospitals NHS Trust · NCT06728956 · Data updated 2026-11-12

This study is testing an online program to help people with Multiple Sclerosis build resilience and confidence to prevent job loss.

Quick facts

Study typeInterventional
Ages18 Years to 66 Years
SexAll
Enrollment300 (estimated)
SponsorThe Leeds Teaching Hospitals NHS Trust
Academic / other
Locations1 site (Leeds)
StatusRecruiting
StartedJune 14, 2024
Main results expectedJuly 1, 2027
Study endsJuly 1, 2027
Registry record updatedDecember 11, 2024
Trial IDNCT06728956 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and over with a clinical diagnosis of Multiple Sclerosis who are currently employed and intend to remain in their jobs for at least six months.

Probably not a fit

Patients who are planning to leave their job within the next six months or lack access to the necessary technology for participation may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of an online Acceptance and Commitment Therapy (ACT) program called 'READY for MS', designed to improve psychological flexibility and self-efficacy in individuals with Multiple Sclerosis (PwMS) who are at risk of job loss. The program can be accessed via computer or mobile device, allowing participants to engage without needing to travel for in-person therapy. The research aims to train healthcare professionals to deliver this program effectively and assess its impact on work stability among PwMS. Participants will complete online questionnaires at various stages, and a subset will participate in interviews to provide qualitative insights into the program's implementation.

Why it matters

Potential benefit: If successful, this program could help PwMS maintain their employment and improve their overall quality of life.

How similar studies have gone: Other studies have shown promise in using online psychological interventions for chronic conditions, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants capable of giving informed consent
* Age 18 years or above
* Currently in paid employment with an intention to remain in employment for at least 6 months
* Phase 2: A registered healthcare professional or allied health professional who works in direct contact with patients diagnosed with Multiple Sclerosis OR
* Phase 3: An individual with a clinical diagnosis of Multiple Sclerosis and reporting a WI score ≥11/22 (on MS-WIS)

Exclusion Criteria:

* Individuals lacking capacity to give informed consent
* Individuals intending to leave paid employment within the next 6 months
* Individuals who will not have access to a device used to access the internet (e.g.

laptop or smartphone) for the duration of study participation

Where it's running

  • Leeds Teaching Hospitals NHS Trust
    Leeds, United Kingdom
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.