Online program to promote physical activity in people with Multiple Sclerosis

Developing A Person-centered Internet-based Health Action Process Approach to Promoting Physical Activity in People With Multiple Sclerosis

Not applicable Interventional University of Illinois at Urbana-Champaign · NCT05124522

This study tests an online program designed to help people with Multiple Sclerosis become more active and see if it encourages them to exercise more regularly.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Illinois at Urbana-Champaign Academic / other
Locations1 site (Champaign, Illinois)
Trial IDNCT05124522 on ClinicalTrials.gov

What this trial studies

This study implements an internet-based intervention called the Health Action Process Approach (eHAPA-MS) aimed at encouraging physical activity among individuals with Multiple Sclerosis. Participants will be randomized into intervention or control groups and will complete surveys and wear accelerometers to monitor their activity levels. The effectiveness and adherence to the program will be assessed over the intervention period. The study targets individuals who have not been physically active for a specified duration and are relapse-free.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older with any type of Multiple Sclerosis who have low physical activity levels and reliable internet access.

Not a fit: Patients who are wheelchair-bound, bedridden, or have high leisure activity levels may not benefit from this intervention.

Why it matters

Potential benefit: If successful, this intervention could significantly improve physical activity levels and overall health in individuals with Multiple Sclerosis.

How similar studies have performed: Other studies have shown promise in using internet-based interventions to promote physical activity, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* are 18 years old and above;
* any type of multiple sclerosis
* have not maintained 30 minutes of MVPA accumulated per day for 2 days of the week during the previous 6 months;
* be relapse-free for the past 30 days;
* show low risk for contraindications of physical activity indicated by no more than a single 'yes' response on the Physical Activity Readiness Questionnaire;
* be able to walk with or without an assistive device;
* are willing to be randomized to an intervention or control group, complete the surveys and questionnaires, and wear an accelerometer during the intervention period;
* have a reliable Internet access.

Exclusion Criteria:

* have a score \>14 for the leisure score index of the Godin Leisure-Time Exercise Questionnaire;
* No computer or mobile device access with the internet.
* Patient determined disease steps (PDDS) Score = 7 i.e., using a wheelchair or scooter most of the time, or PDDS Score = 8 being bedridden.
* Anyone living outside of the United States of America.
* Anyone who is unable to speak, read and write in English.
* not willing to be randomized to an intervention or control group, complete the surveys and questionnaires, and wear an accelerometer during the intervention period.

Where this trial is running

Champaign, Illinois

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Multiple SclerosisPhysical ActivityInternet-Based Intervention
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.